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Taking or using terbinafine with other medicines and herbal supplements - Brand names: Lamisil, Lamisil Once

Cautions with other medicines

Terbinafine cream, gel, sprays and solution are generally OK to use when taking other medicines.

However, terbinafine tablets and some medicines can affect each other. If you're prescribed the tablets, tell your doctor if you're taking:

  • antidepressants
  • beta blockers for heart problems
  • oral contraception
  • amiodarone, to treat heart problems
  • ciclosporin, used after an organ transplant
  • cimetidine, to treat stomach problems such as indigestion
  • rifampicin, to treat bacterial infections
  • tamoxifen, to treat breast cancer
  • warfarin, to treat and prevent blood clots

These are not all the medicines that can affect terbinafine. For a full list, check the leaflet that comes with your medicine.

Taking terbinafine with painkillers

It's safe to take or use terbinafine with paracetamol, ibuprofen, diclofenac or naproxen.

However terbinafine tablets can affect:

  • codeine – terbinafine tablets can affect how well codeine works. If you notice your pain is not as well controlled as usual ask your doctor about other painkillers you could use
  • tramadol – terbinafine tablets can increase your chance of getting side effects from tramadol. Speak to your doctor if you get side effects or feel unwell in any other way

Mixing terbinafine with herbal remedies and supplements

There's not enough information to say that complementary medicines, herbal remedies and supplements are safe to take with terbinafine. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.

Important: Medicine safety

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.

Page last reviewed: 24 March 2023
Next review due: 24 March 2026