Taking perindopril with other medicines and herbal supplements

Cautions with other medicines

There are some medicines that may affect the way perindopril works.

Tell your doctor if you're taking other medicines, including:

• anti-inflammatory medicines such as ibuprofen, indomethacin or aspirin for pain relief (low-dose aspirin – 75mg a day, is safe to take with perindopril)
• medicines to treat low blood pressure, heart failure, asthma or allergies, such as ephedrine, noradrenaline or adrenaline
• medicines to treat high blood pressure, such as aliskeren
• medicines that increase the risk of angioedema, such as valsartan and vidagliptin
• other medicines that can lower your blood pressure, such as some antidepressants, nitrates (for chest pain), baclofen (a muscle relaxant), anaesthetics or medicines for an enlarged prostate gland
• medicines that reduce the activity of your immune system, such as ciclosporin and tacrolimus
• medicines that make you pee more (diuretics), such as furosemide
• medicines that can increase the amount of potassium in your blood, such as spironolactone, triamterene, amiloride, potassium supplements, trimethoprim (for infections) or heparin (for preventing blood clots)
• steroid medicines such as prednisolone
• allopurinol, for gout
• procainamide, for heart rhythm problems
• medicines for diabetes
• lithium, for mental health problems

These are not all the medicines that may cause problems if you take them with perindopril. For a full list, see the leaflet inside your medicine packet.

Mixing perindopril with herbal remedies or supplements

There's not enough information to say that complementary medicines and herbal remedies are safe to take with perindopril. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.