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Who can and cannot take mirtazapine

Who can take mirtazapine

Most adults can take mirtazapine.

If you have diabetes, mirtazapine can make it more difficult to keep your blood sugar stable. Your doctor may recommend that you monitor your blood sugar more often for the first few weeks of taking it and adjust your diabetes treatment if necessary.

Who may not be able to take mirtazapine

Mirtazapine is not suitable for some people. To make sure it's safe for you, tell your doctor before starting to take mirtazapine if you:

  • have ever had an allergic reaction to mirtazapine or any other medicine
  • have a heart problem as mirtazapine can cause low blood pressure
  • have ever taken any other medicines for depression – some rarely used antidepressants can interfere with mirtazapine to cause very high blood pressure even a few weeks after you've stopped taking them
  • have glaucoma – mirtazapine can increase the pressure in your eye
  • have epilepsy – although it's rare, mirtazapine may increase your risk of having a seizure
  • are trying to get pregnant, already pregnant or breastfeeding

Page last reviewed: 15 February 2022
Next review due: 15 February 2025