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Who can and cannot take tibolone - Brand name: Livial

Who can take tibolone

You can usually take tibolone if you:

  • have menopause symptoms and had your last period more than 1 year ago
  • had your last period more than 1 year ago and are at high risk of fractures, and cannot take other medicines for preventing osteoporosis
  • have had menopause caused by surgery to remove your ovaries
  • are taking medicines called gonadorelin analogues for endometriosis

Who may not be able to take tibolone

Tibolone is not suitable for everyone. To make sure it's safe for you, tell your doctor if you:

  • have ever had an allergic reaction to tibolone or any other medicine
  • have ever had breast cancer, are having tests for breast cancer, or are considered high risk due to family history
  • have a type of cancer that is sensitive to oestrogens, such as cancer of the womb lining (endometrium), or if you're having tests for this
  • have any unexplained vaginal bleeding
  • have too much thickening of the womb lining (endometrial hyperplasia) that is not being treated
  • have ever had a blood clot in a vein (thrombosis), such as in your legs (deep vein thrombosis) or your lungs (pulmonary embolism)
  • have a condition that affects how your blood clots, such as protein C, protein S, or antithrombin deficiency
  • have or recently had a condition caused by blood clots in the arteries, such as a heart attack, stroke or angina
  • have ever had liver disease and your liver function tests are not back to normal
  • have a rare inherited condition called porphyria
  • have a rare inherited problem of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption
  • are pregnant or breastfeeding

Page last reviewed: 5 January 2023
Next review due: 5 January 2026