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Taking doxazosin with other medicines and herbal supplements

Cautions with other medicines

There are some medicines that can affect the way doxazosin works.

Tell your doctor or pharmacist if you're taking:

  • medicines for erectile dysfunction, such as sildenafil, tadalafil or vardenafil
  • other medicines for high blood pressure – when taking doxazosin they can sometimes lower your blood pressure too much
  • other medicines that can lower your blood pressure – this includes some antidepressants, muscle relaxants like baclofen, medicines for chest pain like nitrates, and medicines for Parkinson's disease like co-careldopa or levodopa
  • ketoconazole, a medicine usually used for fungal infections

Taking doxazosin with painkillers

Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, may increase your blood pressure, so it's best to keep them to a minimum.

You can take paracetamol or codeine safely with doxazosin.

Mixing doxazosin with herbal remedies and supplements

There's not enough information to say that herbal remedies and supplements are safe to take with doxazosin. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.

Important: Medicine safety

Tell your doctor or pharmacist if you're taking any other medicines, including herbal medicines, vitamins or supplements.

Page last reviewed: 2 March 2022
Next review due: 2 March 2025