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About Pepto-Bismol - Other brand names: Pepti-Calm

Bismuth subsalicylate is the main ingredient in Pepto-Bismol. This medicine is used for heartburn and acid reflux, indigestion, diarrhoea and feeling sick (nausea).

It works by forming a protective coating in your stomach, the lower part of your food pipe and your gut.

Pepto-Bismol comes as tablets and a liquid that you swallow. You can buy it from pharmacies and shops.

Key facts

  • You can take Pepto-Bismol with or without food.
  • It should work within 30 to 60 minutes. You can take up to 8 doses in 24 hours.
  • Speak to a doctor if your symptoms are no better after 2 days.
  • You're unlikely to get any side effects from Pepto-Bismol if you follow the instructions for taking it.
  • If you're allergic to aspirin (or any of the ingredients in Pepto-Bismol) check with a pharmacist before taking this medicine.

Page last reviewed: 3 August 2022
Next review due: 3 August 2025