Cautions with other medicines
Some medicines and lansoprazole can affect each other and make you more likely to have side effects or stop one of the medicines working as well.
Antacids can reduce the amount of lansoprazole that the body takes in so it does not work as well. To stop this happening, if you need to take an antacid, take it at least 2 hours before or after your dose of lansoprazole.
Tell your doctor before you start taking lansoprazole if you're taking any other medicines including:
- digoxin, a heart medicine
- antifungal medicines such as itraconazole or posaconazole
- methotrexate, a medicine that treats psoriasis and rheumatoid arthritis
- HIV medicines
- rifampicin, an antibiotic
- warfarin, to prevent or treat blood clots
- fluvoxamine, an antidepressant
- tacrolimus, to treat eczema or after an organ transplant
These are not all the medicines that may not mix well with lansoprazole. For a full list see the leaflet inside your medicines packet.
Mixing lansoprazole with herbal remedies and supplements
Do not take St John's wort, the herbal remedy for depression, while you're taking lansoprazole. St John's wort may stop lansoprazole working as well as it should.
There's not enough information to say that other complementary medicines and herbal remedies are safe to take with lansoprazole. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.
Important: Medicine safety
Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.