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Common questions about hydrocortisone for skin - Brand names: Dermacort, Derma Care, HC45

How does hydrocortisone work?

Hydrocortisone is a steroid (also called a corticosteroid). Steroids help to reduce swelling (inflammation) in the skin (and other parts of the body).

Skin gets inflamed when an allergic reaction or irritation causes chemicals to be released in the skin. These make blood vessels widen and the irritated skin becomes red, swollen, itchy and painful.

Hydrocortisone skin treatments work on your skin's cells to stop these chemicals being released. This reduces symptoms like swelling, redness and itching.

When will my skin get better?

Your skin should start to get better after using hydrocortisone for a few days.

If you're using a treatment you've bought from a pharmacy or shop, speak to your doctor if you still have symptoms after 1 week, or if your skin gets worse at any time.

Are there any long-term side effects?

Using hydrocortisone for a long time without stopping can mean some of the medicine gets into your blood.

If this happens, there's a very small chance it can cause serious side effects, such as adrenal gland problems, high blood sugar (hyperglycaemia), or problems with your eyesight.

Using it for a long time can also increase the risk of having a reaction when you stop using it. You might have a burning feeling and redness, although this may be more difficult to see on brown or black skin.

The reaction will feel different to the skin condition you have been using hydrocortisone for. It may cover a larger area than the area you were treating.

If you've been using hydrocortisone for a long time, your doctor may tell you to gradually reduce the amount you use before stopping completely.

Can I use hydrocortisone skin treatments on my face?

Do not use hydrocortisone cream, ointment or lotion on your face unless a doctor has advised you to and given you a prescription for it.

The skin on your face is delicate, and if hydrocortisone damages it, it's particularly noticeable.

Some common skin problems that affect the face, such as impetigo, rosacea and acne, can be made worse by hydrocortisone.

If your doctor has prescribed hydrocortisone for your face, follow their instructions carefully.

Do not put hydrocortisone near your eyes or on your eyelids.

Can I still have vaccinations?

Using hydrocortisone skin treatments does not stop you or your child having vaccinations.

But tell the doctor or nurse that you're using hydrocortisone so they can give the vaccine in an untreated area of skin.

Will it affect my contraception?

Hydrocortisone for skin does not affect any types of contraception, including the combined pill or emergency contraception.

Can I drive or ride a bike?

Hydrocortisone does not make you sleepy, so it's safe to drive, ride a bike, or use tools and machinery when using this medicine.

Can I drink alcohol while using hydrocortisone for skin?

Yes, you can drink alcohol while using hydrocortisone skin treatments.

Is there any food or drink I need to avoid?

No, you can eat and drink normally while using hydrocortisone skin treatments.

Page last reviewed: 22 December 2023
Next review due: 22 December 2026