Skip to main content

Side effects of co-dydramol - Brand names: Paramol, Remedeine, Remedeine Forte

Like all medicines, co-dydramol can cause side effects, although not everyone gets them. Many people have no side effects or only minor ones.

You're are more likely to have side effects if you take the higher strengths of co-dydramol.

Common side effects

These common side effects of co-dydramol happen to more than 1 in 100 people. There are things you can do to help cope with them:

Constipation

Eat more high-fibre foods, such as fresh fruit and vegetables, and cereals. Try to drink several glasses of water or another non-alcoholic liquid each day. If you can, try to exercise more regularly, for example, by going for a daily walk or run.

Feeling or being sick (nausea or vomiting)

Try taking co-dydramol with or just after a meal or snack. Stick to simple meals and do not eat rich or spicy food. If you're being sick, try small frequent sips of water to avoid dehydration.

Feelings of sickness should normally wear off after a few days. Talk to your doctor about taking an anti-sickness medicine if it carries on for longer.

If you take the combined contraceptive pill or progestogen-only pill and you're being sick, your contraception may not protect you from pregnancy. Check the pill packet for advice.

Feeling sleepy

Do not drive, cycle or use tools or machinery if you're feeling this way. Do not drink any alcohol, as this will make you feel more tired.

This side effect should go away within a few days as your body gets used to the dihydrocodeine. Speak to your doctor if it carries on for longer.

Headaches

Make sure you rest and drink plenty of fluids. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller.

Talk to your doctor if the headaches last longer than 3 days or are severe.

Feeling dizzy

If co-dydramol makes you feel dizzy, move slowly and carefully, or lie down until it passes. Avoid coffee, cigarettes , alcohol and recreational drugs. If the dizziness does not get better within a couple of days, speak to a pharmacist or your doctor.

Speak to a doctor or pharmacist if the advice on how to cope does not help and a side effect is still bothering you or does not go away.

Serious side effects

Serious side effects are rare and happen in less than 1 in 100 people.

Tell a doctor or call 111 straight away if you:

  • get a skin rash
  • have difficulty peeing
  • have changes in your eyesight

Serious allergic reaction

In rare cases, it's possible to have a serious allergic reaction (anaphylaxis) to co-dydramol.

Immediate action required: Call 999 now if:

  • your lips, mouth, throat or tongue suddenly become swollen
  • you're breathing very fast or struggling to breathe (you may become very wheezy or feel like you're choking or gasping for air)
  • your throat feels tight or you're struggling to swallow
  • your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
  • you suddenly become very confused, drowsy or dizzy
  • someone faints and cannot be woken up
  • a child is limp, floppy or not responding like they normally do (their head may fall to the side, backwards or forwards, or they may find it difficult to lift their head or focus on your face)

You or the person who's unwell may also have a rash that's swollen, raised, itchy, blistered or peeling.

These can be signs of a serious allergic reaction and may need immediate treatment in hospital.

Long-Term side effects

If you buy co-dydramol from a pharmacy, do not use it for more than 3 days. If your pain has not gone away, talk to a pharmacist or doctor.

If you need to take co-dydramol for a long time, your body can become used to (known as tolerance) the dihydrocodeine in it. That means you need higher doses to control your pain over time.

Some people can become more sensitive to pain (hyperalgesia). If this happens, your doctor will reduce your dose gradually to help these symptoms.

It's possible to become addicted to the dihydrocodeine in co-dydramol. For this reason, your dose will be reviewed to make sure you’re only taking the amount you need to control your pain.

Your treatment plan may include details of how and when you'll stop taking co-dydramol.

If you're having treatment for cancer pain or other severe pain, your pain control will be carefully monitored. Speak to your doctor if you're worried about tolerance, hyperalgesia or becoming addicted.

Other side effects

These are not all the side effects of co-dydramol. For a full list, see the leaflet inside your medicine packet.

Information:

You can report any suspected side effect using the Yellow Card safety scheme.

Visit Yellow Card for further information.

Page last reviewed: 9 August 2023
Next review due: 9 August 2026