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About sumatriptan - Brand names: Imigran, Migraitan, Boots Migraine Relief

Sumatriptan is a medicine to treat migraines and cluster headaches. It does not prevent these conditions.

It's not fully understood what causes migraines and cluster headaches, but it may be due to the temporary widening of blood vessels in your brain. Sumatriptan works by narrowing these blood vessels again.

You'll usually take or use sumatriptan once a migraine or cluster headache has started. It is not a painkiller but you can use this medicine if painkillers or non-steroidal anti-inflammatory drugs (NSAIDs) have not worked.

Sumatriptan comes as tablets, a nasal spray or injection. The nasal spray and injection are used to treat migraines and cluster headaches. The tablets are for migraines only.

Sumatriptan is available on prescription. You can also buy packs containing two, 50mg tablets from a pharmacy without a prescription, but only if you have previously been diagnosed with migraines.

Key facts

  • Take or use sumatriptan as soon as your migraine or cluster headache starts.
  • The tablets usually work within 30 to 60 minutes. The spray and injection work quicker.
  • Common side effects include feeling or being sick, feeling sleepy or feeling dizzy.
  • Do not take migraine medicines such as ergotamine or other triptans when taking sumatriptan. This can increase side effects and the risk of an overdose.
  • Do not have more than 2 injections, 2 doses of nasal spray, or more than 300mg of tablets in 24 hours.

Page last reviewed: 8 December 2022
Next review due: 8 December 2025