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Side effects of mebeverine - Brand names: Colofac, Colofac IBS, Aurobeverine

Like all medicines, mebeverine can cause side effects, although not everyone gets them. Any side effects are likely to be mild and will usually pass quickly.

Mild side effects

It happens rarely, but some people may get a mild itchy skin rash from mebeverine.

If this happens to you, it may help to take an antihistamine, which you can buy from a pharmacy. Check with a pharmacist to see what type is suitable for you.

Stop taking mebeverine if this side effect bothers you or does not go away. Ask a pharmacist or doctor whether they can recommend a different medicine.

Serious allergic reaction

In rare cases, mebeverine can cause a serious allergic reaction (anaphylaxis).

Immediate action required: Call 999 now if:

  • your lips, mouth, throat or tongue suddenly become swollen
  • you're breathing very fast or struggling to breathe (you may become very wheezy or feel like you're choking or gasping for air)
  • your throat feels tight or you're struggling to swallow
  • your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
  • you suddenly become very confused, drowsy or dizzy
  • someone faints and cannot be woken up
  • a child is limp, floppy or not responding like they normally do (their head may fall to the side, backwards or forwards, or they may find it difficult to lift their head or focus on your face)

You or the person who's unwell may also have a rash that's swollen, raised, itchy, blistered or peeling.

These can be signs of a serious allergic reaction and may need immediate treatment in hospital.

Other side effects

These are not all the side effects of mebeverine. For a full list, see the leaflet inside your medicines packet.

Information:

You can report any suspected side effect using the Yellow Card safety scheme.

Visit Yellow Card for further information.

Page last reviewed: 17 February 2023
Next review due: 17 February 2026