Taking levetiracetam with other medicines and herbal supplements

Cautions with other medicines

Some medicines can affect the way that levetiracetam works, and increase your chance of side effects.

Your doctor may need to change your dose of levetiracetam if you're taking any of these:

• macrogol, a laxative
• other epilepsy medicines, such as carbamazepine, lamotrigine, oxcarbazepine, phenobarbital or phenytoin
• methotrexate, a medicine that can be used to treat arthritis and other conditions

Mixing levetiracetam with herbal remedies and supplements

There might be a problem taking some herbal remedies and supplements alongside levetiracetam, especially ones that make you feel sleepy or dizzy. Ask your pharmacist for advice.

Some people take vitamin B6 (also known as pyridoxine) alongside levetiracetam to reduce the chances of mood changes. A few studies have reported that it might be helpful, but we do not have enough information to be sure.

If you want to take any vitamins alongside your prescribed medicines, it's important to speak to your pharmacist or doctor, who can advise what you can take.

There's not enough information to say that other complementary medicines and herbal remedies are safe to take with levetiracetam. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.