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Taking continuous combined HRT with other medicines and herbal supplements - Brand names: Evorel Conti, Kliovance, Kliofem, Femoston Conti, FemSeven Conti

Cautions with other medicines

There are some medicines that may affect how continuous combined HRT tablets and capsules work because they can sometimes cause irregular bleeding. HRT can also affect how some medicines work by making them less effective. For example, some HRT can cause epilepsy to be less well controlled.

Tell your doctor or pharmacist if you're taking any other medicines, including:

  • epilepsy medicines
  • some antibiotics
  • medicines for tuberculosis
  • medicines for HIV

HRT skin patches are less likely to be affected by other medicines.

Mixing continuous combined HRT with herbal remedies and supplements

St John's wort may stop HRT tablets and capsules from working as well. HRT patches will be less affected by this.

It's not possible to say that other herbal remedies and supplements are safe to take with HRT. They're not tested in the same way as pharmacy or prescription medicines. They're generally not tested for the effect they can have on other medicines.

Any herbal product may affect other medicines you're taking, so it's important to check with your doctor or pharmacist before starting to take them.

Important: Medicine safety

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.

Page last reviewed: 18 January 2023
Next review due: 18 January 2026