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Docusate - Brand names: Dulcoease, Dioctyl, Norgalax

On this page

  1. About docusate
  2. Key facts
  3. Who can and cannot take docusate
  4. How and when to take docusate
  5. Side effects
  6. How to cope with side effects of docusate
  7. Pregnancy and breastfeeding
  8. Cautions with other medicines
  9. Common questions about docusate

1. About docusate

Docusate is a laxative that is used to treat constipation (difficulty pooing). It helps to soften your poo and makes your bowel movements easier.

It is helpful when you have difficulty going to the toilet because of dry poos or piles (haemorrhoids) or if you have a tear in the lining of your anus (an anal fissure).

You may also be given docusate if you're going to have an x-ray of your stomach. It can help you empty your bowels beforehand.

Docusate comes as capsules and as a liquid that you swallow. It also comes as an enema – a tube of liquid medicine which you squeeze into your anus.

Docusate is available on prescription. You can also buy it from pharmacies.

2. Key facts

  • Docusate capsules and liquid take 1 or 2 days to work.
  • The enema usually works within 20 minutes – so it's best to stay close to a toilet.
  • Do not give docusate to a child under 12 years old unless their doctor prescribes it.
  • Do not take it for more than a week without talking with your doctor.

3. Who can and cannot take docusate

Most adults can safely take docusate, but do not give it to a child under 12 years old unless their doctor prescribes it.


Never give docusate to a child under 12 years old unless their doctor prescribes it.

Docusate is not suitable for some people. To make sure it is safe for you, tell your doctor or pharmacist if you have:

  • ever had an allergic reaction to docusate or any other medicines in the past
  • ever had an allergic reaction to fructose or sorbitol (types of sugar)
  • a blockage in your gut (intestine)
  • stomach pains
  • been feeling sick in the last 24 hours or have been sick
  • been taking a mineral oil laxative such as liquid paraffin

Do not use an enema containing docusate if you have:

4. How and when to take docusate

Docusate comes as capsules, liquid and an enema.

How to take it

  • Capsules – swallow the capsule whole with plenty of water.
  • Liquid – this comes with a plastic cup or spoon to measure the dose. Do not use a kitchen spoon as it will not give the right amount. If you do not have a cup or spoon, ask your pharmacist for one. When you've swallowed it, drink plenty of water or another drink, such as milk or orange juice.
  • Enema – squeeze the tube of liquid gently into your anus. The information leaflet which comes with your docusate will explain how to do this.

Docusate does not usually upset your stomach. You can take the capsules or liquid with or without food. Try to take them at regular intervals throughout the day. Mealtimes (breakfast, lunch and dinner) are useful reminders.

There is no specific time of day to use an enema but it works quickly (usually between 5 and 20 minutes), so use it when you know you'll be near a toilet.

How much to take

  • Capsules – the normal dose is 1 capsule 3 times a day. Do not take more than 5 capsules in a day.
  • Liquid – the normal dose is 2 or 3 x 5ml spoonfuls. Take this dose 3 times a day.
  • Enema – normally 1 tube of liquid is all you need. If you need a second dose, you can use it later in the day or the next day.

You should feel more comfortable within 1 or 2 days of treatment. Reduce the dose as your condition gets better.

Drink plenty of fluids (6 to 8 glasses a day) while you are taking docusate or your constipation may get worse.

What if I forget to take it?

If you forget a dose of docusate, do not worry, just take the next dose as normal.

Never take 2 doses at the same time. Never take an extra dose to make up for a forgotten one.

What if I take too much?

Taking an extra dose of docusate is unlikely to harm you but you should drink lots of water. You may get diarrhoea and stomach pain but this should get better within 1 or 2 days.

If you're worried, talk to your doctor or pharmacist for advice.

5. Side effects

Like all medicines, docusate may cause side effects in some people but most people have no side effects or only minor ones.

Common side effects

If you get any of these side effects, talk to your doctor or pharmacist:

  • feeling sick (nausea)
  • diarrhoea
  • stomach cramps

These side effects are mild and usually go away after a couple of days.

With the docusate enema sometimes people get a burning or pain around their anus. Occasionally the wall of the anus may bleed. This is a reaction to the enema and it should clear up quickly. If the pain or bleeding does not go away or you are worried about them, talk to your doctor or pharmacist.

Serious side effects

In rare cases, it's possible to have a serious allergic reaction (anaphylaxis) to docusate.

Immediate action required: Call 999 or go to A&E if:

  • you get a skin rash that may include itchy, red, swollen, blistered or peeling skin
  • you're wheezing
  • you get tightness in the chest or throat
  • you have trouble breathing or talking
  • your mouth, face, lips, tongue or throat start swelling

You could be having a serious allergic reaction and may need immediate treatment in hospital.

These are not all the side effects of docusate. For a full list see the leaflet inside your medicines packet.


You can report any suspected side effect using the Yellow Card safety scheme.

Visit Yellow Card for further information.

6. How to cope with side effects of docusate

What to do about:

  • feeling sick – try taking docusate with meals or mixing your dose with some water or fruit juice.
  • diarrhoea – drink plenty of water or other fluids. It may also help to take an oral rehydration drink to prevent dehydration. You can buy sachets of powder from a pharmacy which you mix with water. Reducing the dose of docusate may also help diarrhoea. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor.
  • stomach cramps – if you get stomach cramps, reduce your dose of docusate until it goes away.

7. Pregnancy and breastfeeding

Docusate may not be suitable if you're pregnant or breastfeeding because small amounts might be absorbed by your gut.

If you're pregnant or breastfeeding, it's always better to try to treat constipation without taking a medicine. Your doctor or midwife will first advise you to eat more fibre and drink plenty of fluids. It may also help to do gentle exercise.

If diet and lifestyle changes do not work, your doctor or midwife may recommend a laxative, such as lactulose or Fybogel. These are safer laxatives to take during pregnancy and while breastfeeding.

Non-urgent advice: Tell your doctor if you're:

  • trying to get pregnant
  • pregnant
  • breastfeeding

8. Cautions with other medicines

Do not take docusate with a mineral oil laxative such as liquid paraffin.

Mixing docusate with herbal remedies and supplements

There's very little information about taking herbal remedies and supplements with docusate.


For safety, tell your doctor or pharmacist if you're taking any other medicines, including herbal medicines, vitamins or supplements.

9. Common questions about docusate

How does docusate work?

Docusate helps to soften your poo by increasing the amount of water in it. This makes it easier for you to go to the toilet.

Docusate also stimulates the muscles that line your gut, helping them to move poo along your bowel to your anus.

When will I feel better?

Docusate capsules and liquid normally take 1 or 2 days to work. The enema usually works within 20 minutes, so it's best to stay close to a toilet.

Talk to your doctor or pharmacist if you are still constipated after a week.

How long willI take docusate for?

Take docusate for up to 1 week. If you take docusate for longer, your bowel can start to rely on it, rather than working on its own.

If you are still constipated after taking docusate for a week, talk to your doctor.

If your constipation is caused by an illness or a medicine you're taking, your doctor will advise you about when it's best to stop taking docusate.

Is it safe to take docusate for a long time?

Ideally, it's best to use docusate occasionally and for a few days at a time.

Using laxatives like docusate for longer can lead to long term diarrhoea. They can also cause an electrolyte imbalance. This means that levels of substances like sodium, potassium and magnesium in your body get too high or too low. A severe electrolyte imbalance can cause serious health problems such as muscle spasm and twitching, and even fits or seizures.

Using docusate for many weeks, even months, could also stop your bowel working properly on its own.

Can I take different laxatives together?

For most people, 1 laxative will be enough to relieve constipation.

Occasionally, you may need to take 2 different types of laxatives at the same time to get your bowels moving again.

Only take 2 laxatives together on the advice of your doctor or pharmacist as there is an increased risk of side effects.

Are other laxatives any better?

There are other types of laxative. They work in a different way to docusate but are equally good at treating constipation.

  • Bulk-forming laxatives, for example Fybogel and methylcellulose. These increase the 'bulk' or weight of poo which in turn stimulates bowel movement. They take 2 or 3 days to work.
  • Osmotic laxatives, for example lactulose. These draw water from the rest of the body into your bowel to soften your poo and make it easier to pass. They take at least 2 days to work.
  • Stimulant laxatives, for example senna. These stimulate the muscles that line your gut, helping them to move poo along your gut to your anus. Senna takes about 8 hours to work.
Is there any food or drink I need to avoid?

You can eat and drink normally while taking docusate.

It might be a good idea to stop eating pastries, puddings, sweets, cheese and cake for a while as these foods can make constipation worse.

Can I drink alcohol with it?

Yes, you can drink alcohol with docusate.

Can I use docusate after surgery?

It's quite common to have constipation after surgery. Using a laxative may help relieve the discomfort.

If you have constipation after an operation, it's better to use lactulose because it is gentler than docusate. You can get it from pharmacies.

Can lifestyle changes help constipation?

It's often possible to improve constipation without having to use laxatives. Before trying docusate – or to stop constipation coming back – it may help to:

  • eat more fibre – aim for about 30g of fibre a day. High-fibre foods include fruit, vegetables and cereals. If you're not used to a high-fibre diet, increase the amount of fibre you eat gradually.
  • add bulking agents, such as wheat bran, to your diet. These will help make your poo softer and easier to pass (although bran and fibre can sometimes make bloating worse).
  • drink plenty of water – to keep poo soft
  • exercise regularly – keeping your body active will help to keep your gut moving

Page last reviewed: 29 January 2018
Next review due: 29 January 2021