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Side effects of clotrimazole cream, spray and solution - Brand name: Canesten

Like all medicines, clotrimazole can cause side effects, although not everyone gets them. Side effects usually go away when you stop using it.

Common side effects

Clotrimazole cream, spray or solution can sometimes cause irritated or red skin, or pain or a burning or stinging feeling when you put it on.

If you get these side effects and they do not go away, talk to your pharmacist or doctor.

Serious allergic reaction

In rare cases, it's possible to have a serious allergic reaction (anaphylaxis) to clotrimazole.

Immediate action required: Call 999 now if:

  • your lips, mouth, throat or tongue suddenly become swollen
  • you're breathing very fast or struggling to breathe (you may become very wheezy or feel like you're choking or gasping for air)
  • your throat feels tight or you're struggling to swallow
  • your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
  • you suddenly become very confused, drowsy or dizzy
  • someone faints and cannot be woken up
  • a child is limp, floppy or not responding like they normally do (their head may fall to the side, backwards or forwards, or they may find it difficult to lift their head or focus on your face)

You or the person who's unwell may also have a rash that's swollen, raised, itchy, blistered or peeling.

These can be signs of a serious allergic reaction and may need immediate treatment in hospital.

Other side effects

These are not all the side effects of clotrimazole. For a full list, see the leaflet inside your medicine packet.

Information:

You can report any suspected side effect using the Yellow Card safety scheme.

Visit Yellow Card for further information.

Page last reviewed: 24 October 2022
Next review due: 24 October 2025