Taking clonazepam with other medicines and herbal supplements

Cautions with other medicines

Some medicines affect the way clonazepam works and increase the chance of you having side effects.

Before you start taking clonazepam, tell a doctor if you're taking any of these medicines:

• anticonvulsants, used to treat epilepsy
• antipsychotics or antidepressants, used to treat mental health problems and depression
• hypnotics, used to treat anxiety or sleep problems
• medicines used to treat muscle spasms, such as baclofen or tizanidine
• medicines used to lower blood pressure, including ACE inhibitors such as enalapril or lisinopril, calcium channel blockers such as amlodipine or felodipine, or diuretics such as indapamide or bendroflumethiazide
• drowsy (sedating) antihistamines, such as chlorphenamine or promethazine
• strong painkillers such as codeine, methadone, morphine, oxycodone, pethidine or tramadol
• cimetidine, a medicine for stomach problems and heartburn
• rifampicin, a medicine to treat bacterial infections
• antifungal medicines such as fluconazole

Mixing clonazepam with herbal remedies or supplements

Do not take herbal remedies for anxiety or insomnia, such as valerian or passionflower, with clonazepam. They can increase the drowsy effects of clonazepam and may also have other side effects.

There's not enough information to say that other complementary medicines, herbal remedies and supplements are safe to take with clonazepam. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.