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Taking baclofen with other medicines and herbal supplements

Cautions with other medicines

Some medicines and baclofen can affect each other and increase your risk of side effects.

Tell your pharmacist or doctor if you're taking any of these medicines before taking baclofen:

  • other medicines to relax muscles such as tizanidine
  • lithium, a medicine for mental health problems
  • antidepressants such as amitriptyline
  • medicines that lower high blood pressure
  • non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen
  • levodopa, a medicine for Parkinson's disease

Mixing baclofen with herbal remedies and supplements

There's not enough information to say that herbal remedies and supplements are safe to take with baclofen. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.

Important: Medicine safety

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.

Page last reviewed: 25 February 2022
Next review due: 25 February 2025