Cautions with other medicines
Some medicines can affect apixaban. This can lead to serious side effects.
Tell your doctor if you are taking any of these medicines before starting apixaban:
- any other anticoagulant, such as warfarin or enoxaparin
- medicines to treat fungal or bacterial infections, such as ketoconazole, erythromycin, clarithromycin or rifampicin
- medicines to treat an abnormal heartbeat, such as dronedarone, quinidine or verapamil
- medicines to prevent organ rejection after a transplant, such as ciclosporin
- medicines to treat epilepsy, such as carbamazepine, phenytoin or phenobarbital
- non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or aspirin
Taking apixaban with everyday painkillers
You can take paracetamol while you're taking apixaban.
Do not take aspirin or ibuprofen while you're taking apixaban unless a doctor has said it's OK. They increase the chance of bleeding.
Mixing apixaban with herbal remedies and supplements
Do not take St John's wort, the herbal remedy for depression, while you're taking apixaban. It can increase your risk of side effects.
There's not enough information to say that other herbal remedies and supplements are safe to take with apixaban.
They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.
Important: Medicine safety
Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.