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Pregnancy, breastfeeding and fertility while taking allopurinol - Brand names: Zyloric, Uricto

Allopurinol and pregnancy

Allopurinol is not usually recommended during pregnancy. There is not enough evidence to say that it's safe.

Talk to a doctor if you're thinking about trying for a baby. There may be other medicines that are more suitable for you to take during pregnancy.

Allopurinol and breastfeeding

If your doctor or health visitor says your baby is healthy, you can take allopurinol while you're breastfeeding.

There is not much information about using allopurinol while breastfeeding, but it is likely that allopurinol passes into breast milk in small amounts

If you notice that your baby is not feeding as well as usual, is being sick (vomiting), has diarrhoea or a rash, or if you have any other concerns about your baby, then talk to your doctor, pharmacist, midwife or health visitor.

Allopurinol and fertility

There is no evidence to suggest that taking allopurinol reduces fertility in either men or women. However, talk to a doctor if you want to try for a baby while taking allopurinol.

Non-urgent advice: Tell your doctor if you're:

  • trying to get pregnant
  • pregnant
  • breastfeeding

Find out more about how allopurinol can affect you and your baby during pregnancy on the Best Use of Medicines in Pregnancy (BUMPS) website.

Page last reviewed: 23 January 2023
Next review due: 23 January 2026