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Medicines for high cholesterol - High cholesterol

Medicine to lower your cholesterol

You might need medicine to lower your cholesterol if:

  • your cholesterol level has not gone down after changing your diet and lifestyle
  • you're at a high risk of having a heart attack or stroke

Ask your doctor about the medicines you can take.

Statins

Statins are the most common medicine for high cholesterol.

They reduce the amount of cholesterol your body makes.

You take a tablet once a day. You usually need to take them for life.

Other medicines for high cholesterol

Other medicines may be used if statins do not work or you cannot take statins.

These include:

  • other tablets – such as ezetimibe, sometimes with bempedoic acid
  • injections – such as alirocumab, evolocumab and inclisiran
Information:

Find out more

HEART UK: treatment for high cholesterol

Page last reviewed: 13 March 2026
Next review due: 13 March 2029