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Pepto-Bismol (bismuth subsalicylate)

Pepto-Bismol (bismuth subsalicylate) is a medicine that treats symptoms of indigestion, heartburn and diarrhoea. You can buy it from pharmacies and shops.

What Pepto-Bismol is for

Pepto-Bismol (bismuth subsalicylate) is used to treat symptoms such as:

  • indigestion
  • acid reflux and heartburn
  • feeling sick (nausea)
  • diarrhoea

It works by reducing inflammation and forming a protective coating in your stomach, the lower part of your food pipe and your gut.

How to take Pepto-Bismol

Pepto-Bismol (bismuth subsalicylate) usually comes as a liquid you swallow or tablets you chew. You can take it with or without food.

Always check the packet or leaflet that comes with your medicine. Ask a pharmacist or doctor for advice if you're not sure how to take it or have any problems taking it.

How to take different types of Pepto-Bismol

Liquid (17.5 mg/ml oral suspension)

When taking liquid Pepto-Bismol:

  • shake the bottle before use
  • take 30ml at a time using the dosing cup that comes with your medicine
  • wait at least 30 minutes between doses
  • do not take more than 8 doses in 24 hours
Tablets (262.5mg chewable tablets)

When taking Pepto-Bismol tablets:

  • chew 2 tablets, or dissolve them in your mouth
  • wait at least 30 minutes between doses
  • do not take more than 16 tablets in 24 hours

Important

Do not take Pepto-Bismol for more than 2 days unless advised to by a doctor.

Stop taking it and see a GP if your symptoms get worse or do not get better.

If you take too much Pepto-Bismol

Taking an extra dose of Pepto-Bismol is unlikely to cause problems, but it's important to get medical advice if you take too much as it can be dangerous.

Urgent advice: Speak to a pharmacist as soon as possible if:

  • you've taken more Pepto-Bismol than it says on the packet or leaflet
  • you're taking Pepto-Bismol and start hearing ringing or buzzing in your ears (tinnitus)

If you're unable to speak to a pharmacist, or you took too much of your medicine on purpose, call NHS 111 for advice.

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Information:

If you're told to go to A&E, do not drive. Ask someone to drive you or call 999 and ask for an ambulance.

Bring the Pepto-Bismol packet or leaflet inside it, any remaining medicine, and any other medicines you take.

Side effects of Pepto-Bismol

Like all medicines, Pepto-Bismol (bismuth subsalicylate) can cause side effects, although not everyone gets them.

Common side effects

Possible side effects of Pepto-Bismol include:

  • black poo
  • a black tongue

These side effects are harmless and usually go away on their own.

Pepto-Bismol will not usually affect your ability to drive, ride a bike or use machinery.

Non-urgent advice: Speak to a pharmacist or doctor if:

  • you have any side effects that bother you or do not go away

They may be able to give you advice about how to reduce any side effects.

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Serious side effects

In rare cases, Pepto-Bismol can cause a serious allergic reaction.

Symptoms of an allergic reaction (anaphylaxis) include a swollen throat or tongue, a raised, itchy rash and difficulty breathing.

Immediate action required: Call 999 if:

  • you're taking Pepto-Bismol and think you might be having anaphylaxis

Who can and cannot take Pepto-Bismol

Most people aged 16 years or older can take Pepto-Bismol (bismuth subsalicylate).

Do not give Pepto-Bismol to children aged 15 years or under because it can cause a serious condition called Reye's syndrome in rare cases.

Pepto-Bismol is not suitable for everyone. For example, it may not be suitable if you:

  • have had an allergic reaction or serious side effect from bismuth subsalicylate before
  • have had an allergic reaction or serious side effect from aspirin before
  • have blood in your poo
  • have a blood clotting disorder
  • have gout
  • have a stomach ulcer

Check the packet or leaflet that comes with your medicine to see if it's suitable for you. Speak to a pharmacist or doctor if you're not sure if you can use it.

Breastfeeding and Pepto-Bismol

Pepto-Bismol is not usually recommended if you're breastfeeding.

Check with a pharmacist or doctor before using Pepto-Bismol while you're breastfeeding. They may be able to recommend a different medicine.

Pregnancy and Pepto-Bismol

Pepto-Bismol is not usually recommended during pregnancy.

Talk to a doctor or pharmacist before taking Pepto-Bismol while you're pregnant. They may be able to recommend a different medicine.

Taking Pepto-Bismol with other medicines, food and drink

There are some medicines, remedies and supplements that may not mix well with Pepto-Bismol (bismuth subsalicylate).

These include:

Check the packet or leaflet that comes with your medicine to see if it's suitable for you. Speak to a pharmacist or doctor if you're not sure if you can take it.

Food, drink and alcohol with Pepto-Bismol

You can eat and drink as usual when taking Pepto-Bismol.

Information:

Find out more about your medicine

To find out more about your medicine, you can:

  • check the leaflet that comes with it
  • speak to a pharmacist or doctor for advice

Page last reviewed: 27 August 2026
Next review due: 27 August 2029

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