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About Pepto-Bismol - Other brand names: Pepti-Calm

Bismuth subsalicylate is the main ingredient in Pepto-Bismol. This medicine is used for heartburn and acid reflux, indigestion, diarrhoea and feeling sick (nausea).

It works by protecting your stomach and the lower part of your food pipe from stomach acid. It is also a mild antacid, which helps reduce too much stomach acid and eases any discomfort.

Pepto-Bismol comes as tablets and a liquid that you swallow. You can only buy it from pharmacies.

Key facts

  • You can take Pepto-Bismol with or without food.
  • It should work within 30 to 60 minutes. You can take up to 8 doses in 24 hours.
  • Speak to a doctor if your symptoms are no better after 2 days.
  • You're unlikely to get any side effects from Pepto-Bismol if you follow the instructions for taking it.
  • If you're allergic to aspirin (or any of the ingredients in Pepto-Bismol) check with a pharmacist before taking this medicine.

Page last reviewed: 3 August 2022
Next review due: 3 August 2025