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Taking paracetamol for adults with other medicines and herbal supplements - Brand names: Disprol, Hedex, Medinol, Panadol

Cautions with other medicines

It's safe to take paracetamol with most prescription medicines, including antibiotics.

Paracetamol is not suitable for some people. Talk to your doctor if you take:

  • warfarin, a medicine to prevent blood clots – paracetamol can increase the risk of bleeding if you take it regularly
  • medicine to treat epilepsy
  • medicine to treat tuberculosis (TB)

Taking paracetamol with other painkillers

It's safe to take paracetamol with other types of painkiller that do not contain paracetamol, such as ibuprofen, aspirin or codeine.

Do not take paracetamol alongside other medicines that contain paracetamol. If you take 2 different medicines that contain paracetamol, there's a risk of overdose.

Mixing paracetamol with herbal remedies and supplements

Paracetamol is not generally affected by also taking herbal remedies or supplements.

There's not enough information to say whether complementary medicines, herbal remedies and supplements are safe to take with paracetamol. They're not tested in the same way as pharmacy and prescription medicines. They're generally not tested for the effect they have on other medicines.

Important: Medicine safety

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.

Page last reviewed: 20 October 2022
Next review due: 20 October 2025