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Taking or using metronidazole with other medicines and herbal supplements

Cautions with other medicines

Metronidazole may not mix well with some other medicines. This is not usually a problem when metronidazole is applied to the skin as a gel or cream, but it can be a problem with metronidazole tablets, suppositories, liquid or vaginal gel.

Tell your doctor before you start taking or using metronidazole if you're taking any of these medicines:

  • warfarin, a medicine that helps to treat and prevent blood clots
  • lithium, used to treat some types of mental health conditions
  • disulfiram, used to help people stay off alcohol
  • phenytoin or phenobarbitone, used to treat epilepsy
  • ciclosporin, used to reduce the activity of the immune system
  • fluorouracil or busulfan, used to treat some types of cancer
  • any medicines that you take as a liquid, in case these contain alcohol

Mixing metronidazole with herbal remedies and supplements

There are no known problems with taking herbal remedies and supplements alongside metronidazole. However, some remedies and supplements that come as liquids that you drink may also contain alcohol. Check the list of ingredients or ask the supplier or manufacturer.

Important: Medicine safety

Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.

Page last reviewed: 17 November 2021
Next review due: 17 November 2024