Zocor (zocor 10mg tablets)



Information specific to: zocor 10mg tablets when used in cholesterol.

Zocor (zoh-cor) is a medicine which is used in dyslipidaemia, reducing the chances of a heart attack or stroke in people who have diabetes and reducing the chances of a heart attack or stroke in people who have heart disease. Zocor contains simvastatin. It is supplied by Merck Sharp & Dohme Limited.

The information in this Medicine Guide for zocor varies according to the condition being treated and the particular preparation used.

Your medicine

Zocor reduces the amount of cholesterol produced in the body. Zocor is used to help lower cholesterol in people with high cholesterol.

Some people with type II diabetes have an increased risk of having certain heart and circulation events such as a heart attack or stroke. In these people Zocor may help to reduce the chances of certain heart and circulation events from happening.

People taking Zocor usually need to have a low fat diet which may also help to reduce the amount of cholesterol in their blood.

Other information about Zocor:

  • your prescriber may vary the dose of your medicine to find what is best for you

Do not share your medicine with other people. It may not be suitable for them and may harm them.

The pharmacy label on your medicine tells you how much medicine you should take. It also tells you how often you should take your medicine. This is the dose that you and your prescriber have agreed you should take. You should not change the dose of your medicine unless you are told to do so by your prescriber.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

Whether this medicine is suitable for you

Zocor is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

  • are about to have surgery
  • are aged over 65 years
  • are allergic or sensitive to or have had a bad reaction to statin or a fibrate in the past
  • are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
  • are breast-feeding
  • are female
  • are of asian origin
  • are pregnant
  • are taking fusidic acid or have taken it within the past seven days
  • drink alcohol heavily
  • have galactose intolerance
  • have genetic conditions which reduce the breakdown of Zocor in the body
  • have glucose-galactose malabsorption problems
  • have hypothyroidism
  • have kidney problems
  • have Lapp lactase deficiency
  • have liver problems
  • have or have a family history of muscle disorders
  • have or have had high blood pressure
  • have risk factors for rhabdomyolysis

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for a child who is under 10 years of age or who has not started to go through puberty yet or for females who have not started their periods.

As part of the process of assessing suitability to take this medicine a prescriber may also arrange tests:

  • to determine whether or not the medicine is suitable and whether it must be prescribed with extra care
  • to check that this medicine is not having any undesired effects

Over time it is possible that Zocor can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Zocor has become unsuitable, it is important that the prescriber is contacted immediately.


Alcohol can interact with certain medicines.

In the case of Zocor:

  • this medicine may interact with alcohol

If you choose to drink alcohol while taking this medicine, it is best that you only drink alcohol in moderation. For more advice speak to your prescriber.


Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.

In the case of Zocor:

  • Zocor is not known to interact with food. You should continue on your low fat diet while taking Zocor
  • this medicine interacts with grapefruit juice. Grapefruit juice increases the level of Zocor in your blood

For more advice speak to your prescriber, dietitian or pharmacist.

Driving and operating machinery

When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.

In the case of Zocor:

  • this medicine could affect your ability to drive or operate machinery

You should see how this medicine affects you before you judge whether you are safe to drive or operate machinery. If you are in any doubt about whether you should drive or operate machinery, talk to your prescriber.

Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Zocor:

  • you must not take Zocor during pregnancy. If you could become pregnant, you must use effective contraception or abstain from penetrative sex. You must contact your prescriber if you become pregnant, or think you have become pregnant, while taking Zocor
  • if you are taking Zocor and are planning to have a baby you must contact your prescriber

You should discuss your personal circumstances with your doctor if you are pregnant or want to become pregnant. This is so that together you can make a decision about what treatment you may need during your pregnancy.

You should discuss whether there are any other medicines which you could take during pregnancy which would treat your condition.


Certain medicines can pass into breast milk and may reach your baby through breast-feeding.

In the case of Zocor:

  • it is not known whether this medicine passes into breast milk

Women who are taking Zocor must not breast-feed. If you wish to breast-feed you should discuss with your prescriber whether there are any other medicines you could have. You should not stop this medicine without taking advice from your doctor.

Taking other medicines

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.

The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.

Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.

The following medicines may interact with Zocor:

  • acipimox
  • amiodarone
  • amlodipine
  • boceprevir
  • ciclosporin
  • clarithromycin
  • colchicine
  • danazol
  • diltiazem
  • erythromycin
  • fenofibrate
  • fluconazole
  • fusidic acid
  • gemfibrozil
  • itraconazole
  • ketoconazole
  • nefazodone
  • nelfinavir
  • nicotinic acid
  • posaconazole
  • rifampicin
  • telaprevir
  • telithromycin
  • verapamil
  • voriconazole

The following types of medicine may interact with Zocor:

  • anticoagulants
  • calcium channel blockers
  • cytochrome P450 enzyme inducers
  • cytochrome P450 enzyme inhibitors
  • fibrates
  • HIV protease inhibitors
  • medicines that inhibit organic anion transporting polypeptide B1

If you are taking Zocor and one of the above medicines or types of medicines, make sure your prescriber knows about it.

Complementary preparations and vitamins

Medicines can interact with complementary preparations and vitamins.

Make sure you tell your prescriber the names of all the complementary preparations and vitamins that you are taking or are planning to take.

Your prescriber can then decide whether it is appropriate for you to take combinations that are known to interact.

In the case of Zocor:

  • this medicine may interact with nicotinic acid or preparations containing nicotinic acid

If you have been prescribed Zocor you should only take something on the above list on the specific advice of your prescriber or pharmacist.

Content provided by Datapharm

This medicine is also used for: