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Valdoxan (Valdoxan 25mg tablets)

Side effects

Information specific to: Valdoxan 25mg tablets when used in Depression.


A medicine is only made available to the public if the clinical trials have shown that the benefits of taking the medicine outweigh the risks.

Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated.

Some side-effects may be serious while others may only be a mild inconvenience.

Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.

Common: More than 1 in 100 people who take Valdoxan

  • abnormal laboratory test results
  • back pain
  • constipation
  • diarrhoea
  • difficulty sleeping
  • feeling anxious
  • feeling dizzy
  • headaches
  • increased sweating
  • migraine
  • nausea
  • sleepiness
  • stomach pain - seek immediate medical advice if you have pain on the right side of your stomach
  • tiredness
  • vomiting

Uncommon: More than 1 in 1000 people who take Valdoxan

  • aggressive behaviour
  • blurred vision
  • eczema
  • feeling agitated
  • feeling irritable
  • feeling restless
  • itching
  • nightmares
  • paraesthesiae
  • restless leg syndrome
  • strange dreams
  • tinnitus
  • urticaria

Rare: More than 1 in 10,000 people who take Valdoxan

  • angioedema
  • facial oedema
  • hallucinations
  • liver problems - some of these liver problems may be fatal. Seek immediate medical advice if you develop jaundice, dark urine, light coloured stools, pain in the right side of the stomach or unexplained or unexpected tiredness
  • mania or mania-like behaviour - seek immediate medical advice if you develop mania or mania-like symptoms
  • skin rash or rashes
  • weight gain
  • weight loss

The frequency of these side-effects is unknown

  • suicide attempt or thoughts of committing suicide - you or your carer must seek immediate medical advice if: you have thoughts of committing suicide, you attempt to commit suicide, your symptoms worsen or your behaviour is unusual

The following side effects have been reported in people who have had medicines similar to Valdoxan. The frequency of these side-effects in people who take Valdoxan is not known

  • withdrawal symptoms

If you feel unwell or if you have concerns about a side-effect, you will need to seek advice. If you feel very ill, get medical help straight away. Contact your prescriber, pharmacist, nurse or call 111.

Content provided by Datapharm

Yellow Card scheme

The Yellow card Scheme is vital in helping the MHRA monitor the safety of the medicines and vaccines that are on the market.

Before a medicine is granted a licence so that it can be made available in the United Kingdom, it must pass strict tests and checks to ensure that it is acceptably safe and effective. All effective medicines however, can cause side effects.

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This medicine is also used for: