Norethisterone (Norethisterone 5mg tablets)

 

Overview

Information specific to: Norethisterone 5mg tablets when used in Premenstrual tension.

Norethisterone (Nor-reth-ist-er-rone) is a medicine which is used in a number of conditions - an example is breast cancer.

The information in this Medicine Guide for Norethisterone varies according to the condition being treated and the particular preparation used.

Your medicine

Norethisterone contains a hormone which is similar to the hormoneprogestogen that is naturally produced by the body. It is used to treat a number of menstrual cycle disorders. Norethisterone is also used to help treat breast cancer.

Other information about Norethisterone:

  • it is important for some people to start taking this medicine on a particular day of the menstrual cycle for a specific number of days. This depends on which condition is being treated. For more information about when you should start to take this medicine and for how many days you should take it each month, ask your prescriber, pharmacist or read the patient information leaflet that comes with your medicine
  • once you have finished taking a course of Norethisterone, you will usually have a menstrual bleed a few days after taking your last tablet. If you do not have a menstrual bleed, you must make sure that you are not pregnant before taking any more tablets

Do not share your medicine with other people. It may not be suitable for them and may harm them.

The pharmacy label on your medicine tells you how much medicine you should take. It also tells you how often you should take your medicine. This is the dose that you and your prescriber have agreed you should take. You should not change the dose of your medicine unless you are told to do so by your prescriber.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

Whether this medicine is suitable for you

Norethisterone is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

  • are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
  • are pregnant
  • have conditions which may be worsened by fluid retention such as epilepsy, migraine, asthma, heart or kidney problems
  • have diabetes
  • have had certain problems during pregnancy such as jaundice, rashes or itching
  • have liver problems
  • have or have had thromboembolic problems such as angina, a heart attack, deep vein thrombosis or a pulmonary embolism
  • have porphyria
  • have risk factors for developing bloodclots such as having a personal or family history of bloodclots, having spontaneous miscarriages, being immobile for a long period of time, being obese, having varicose veins, having systemic lupus erythematosus, have recently had surgery or trauma or are about to have surgery
  • have vaginal bleeding and the cause of the bleeding is not known

Over time it is possible that Norethisterone can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Norethisterone has become unsuitable, it is important that the prescriber is contacted immediately.

Alcohol

Alcohol can interact with certain medicines.

In the case of Norethisterone:

  • there are no known interactions between alcohol and Norethisterone

Diet

Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.

In the case of Norethisterone:

  • there are no specific foods that you must exclude from your diet when taking Norethisterone

Driving and operating machinery

When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.

Like all medicinesNorethisterone can cause side effects. You should see how this medicine affects you and then judge if you are safe to drive or operate machinery. If you are in any doubt, talk to your prescriber.

Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Norethisterone:

  • do not take this medicine during pregnancy

This medicine is not suitable during pregnancy. It is very important that you seek urgent medical advice if you become pregnant or think you have become pregnant while taking this medicine.

If you are planning to become pregnant, you should discuss your personal circumstances with your doctor so that together you can make a decision about what treatment you may need during your pregnancy.

Breast-feeding

Certain medicines can pass into breast milk and may reach your baby through breast-feeding.

For information about Norethisterone and breast-feeding, contact your prescriber.

Taking other medicines

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.

The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.

Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.

The following medicines may interact with Norethisterone:

  • aminoglutethimide
  • ampicillin
  • carbamazepine
  • ciclosporin
  • co-trimoxazole
  • efavirenz
  • nelfinavir
  • nevirapine
  • oxacillin
  • phenobarbital
  • phenytoin
  • rifabutin
  • rifampicin
  • ritonavir

The following types of medicine may interact with Norethisterone:

  • anticonvulsants
  • anti-infectives
  • cytochrome P450 enzyme inducers
  • cytotoxics
  • medicines which cause fluid retention such as non-steroidal anti-inflammatories and vasodilators
  • tetracyclines

If you are taking Norethisterone and one of the above medicines or types of medicines, make sure your prescriber knows about it.

Complementary preparations and vitamins

Medicines can interact with complementary preparations and vitamins.

Make sure you tell your prescriber the names of all the complementary preparations and vitamins that you are taking or are planning to take.

Your prescriber can then decide whether it is appropriate for you to take combinations that are known to interact.

In the case of Norethisterone:

  • this medicineinteracts with St. John's Wort

If you have been prescribed Norethisterone you should only take something on the above list on the specific advice of your prescriber or pharmacist.

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