Tramadol Hydrochloride (Tramadol 50mg capsules)

 

Overview

Information specific to: Tramadol 50mg capsules when used in Pain (severe).

Tramadol hydrochloride (Tramme-dol hi-droh-clor-ride) is a medicine which is used in relieving moderate to severe pain.

The information in this Medicine Guide for Tramadol hydrochloride varies according to the condition being treated and the particular preparation used.

Your medicine

Tramadol hydrochloride is a type of strong pain killer. It is used to help relieve moderate to severe pain. It works by affecting chemicals in the brain and nervous system which are involved in the sensation of pain. Tramadol hydrochloride can cause tolerance and dependence in some people.

Other information about Tramadol hydrochloride:

  • your prescriber will try to find the lowest dose of your medicine which can control your condition
  • this medicine must not be used by people who are dependent on opioids and is not suitable for treating the effects of opioid withdrawal

Do not share your medicine with other people. It may not be suitable for them and may harm them.

The pharmacy label on your medicine tells you how much medicine you should take. It also tells you how often you should take your medicine. This is the dose that you and your prescriber have agreed you should take. You should not change the dose of your medicine unless you are told to do so by your prescriber.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

Whether this medicine is suitable for you

Tramadol hydrochloride is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

  • are aged over 75 years
  • are allergic or sensitive to or have had a bad reaction to opiates in the past
  • are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
  • are in shock
  • are intoxicated with alcohol
  • are prone to drug dependence or drug misuse
  • are taking monoamine oxidase inhibitors or have taken them within the last 14 days
  • have head injuries
  • have high intracranial pressure
  • have kidney problems or are on dialysis
  • have liver problems
  • have or have had epilepsy or are prone to seizures or a convulsive disorder
  • have respiratory depression

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for a child who is under the age of 12 years or for someone with reduced consciousness.

Over time it is possible that Tramadol hydrochloride can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Tramadol hydrochloride has become unsuitable, it is important that the prescriber is contacted immediately.

Alcohol

Alcohol can interact with certain medicines.

In the case of Tramadol hydrochloride:

  • alcohol may increase the effects of this medicine

You should seek advice from your prescriber as to whether you may drink alcohol while taking this medicine.

Diet

Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.

In the case of Tramadol hydrochloride:

  • there are no specific foods that you must exclude from your diet when taking Tramadol hydrochloride

Driving and operating machinery

When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.

In the case of Tramadol hydrochloride:

  • this medicine could affect your ability to drive or operate machinery

You should see how this medicine affects you before you judge whether you are safe to drive or operate machinery. If you are in any doubt about whether you should drive or operate machinery, talk to your prescriber.

Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Tramadol hydrochloride:

  • do not take this medicine during pregnancy

You should discuss your personal circumstances with your doctor if you are pregnant or want to become pregnant. This is so that together you can make a decision about what treatment you may need during your pregnancy.

You should discuss whether there are any other medicines which you could take during pregnancy which would treat your condition.

Breast-feeding

Certain medicines can pass into breast milk and may reach your baby through breast-feeding.

In the case of Tramadol hydrochloride:

  • women who are breast-feeding must not take this medicine

Before you have your baby you should discuss breast-feeding with your doctor or midwife. If you wish to breast-feed you should discuss with your prescriber whether there are any other medicines you could take which would also allow you to breast-feed. You should not stop this medicine without taking advice from your doctor.

Taking other medicines

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.

The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.

Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.

The following medicines may interact with Tramadol hydrochloride:

  • buprenorphine
  • bupropion
  • carbamazepine
  • erythromycin
  • ketoconazole
  • mirtazapine
  • nalbuphine
  • ondansetron
  • pentazocine
  • tetrahydrocannabinol
  • warfarin

The following types of medicine may interact with Tramadol hydrochloride:

  • anti-emetics
  • antipsychotics
  • centrally acting analgesics
  • coumarin anticoagulants
  • cytochrome P450 enzyme inhibitors
  • hypnotics
  • liver enzyme inducers
  • medicines that act on the central nervous system
  • medicines that affect seizure control
  • monoamine oxidase inhibitors
  • opioids
  • psychotropics
  • selective serotonin re-uptake inhibitors
  • serotonergics
  • serotonin - norepinephrine reuptake inhibitors
  • tricyclic antidepressants

If you are taking Tramadol hydrochloride and one of the above medicines or types of medicines, make sure your prescriber knows about it.

Complementary preparations and vitamins

Medicines can interact with complementary preparations and vitamins. In general, there is not much information available about interactions between medicines and complementary preparations or vitamins.

If you are planning to take or are already taking any complementary preparations and vitamins you should ask your prescriber whether there are any known interactions with Tramadol hydrochloride.

Your prescriber can advise whether it is appropriate for you to take combinations that are known to interact. They can also discuss with you the possible effect that the complementary preparations and vitamins may have on your condition.

If you experience any unusual effects while taking this medicine in combination with complementary preparations and vitamins, you should tell your prescriber.

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