Painkiller headaches

Painkillers are a good way to relieve headaches, but if you take them more than two or three times a week, they could be the cause of your headaches.

Up to one in 10 people who have frequent headaches do so because they take painkillers too often, says Dr Fayyaz Ahmed, consultant neurologist at Hull Royal Infirmary.

“Around 5% of the patients in my headache clinic have what we call medication-overuse headaches from taking painkillers regularly over a long period. This statistic is probably even higher in the general population, with 5-10% of people with headaches getting them from taking too many painkillers."

Painkiller, or rebound, headaches are frequent or daily headaches that develop after taking painkillers for tension headaches or migraines over several months.

Strangely, painkiller headaches only become a problem in people who take painkillers to treat headaches. They don’t occur in people who take painkillers for long periods for other painful conditions such as arthritis and back pain.

How it happens

“Most people who get medication-overuse headaches aren’t taking more than the recommended dose on the painkiller packet,” says Dr Ahmed. “The problem begins when you take advantage of the recommended dose to take painkillers for long periods, often for months on end.

“If you take painkillers for your headaches more than twice a week for more than three months you'll be at very high risk of getting rebound headaches,” says Dr Ahmed.

What happens is that your body gets used to the painkillers. A rebound headache develops if you don’t take a painkiller within a day or so of the last dose. You assume it’s just another tension headache or migraine and take a further dose of painkiller. When the effect of the painkiller wears off, another rebound headache develops and the cycle continues. Some people even start to take painkillers every day to prevent headaches, which only makes matters worse.

Which painkillers to avoid

All the common painkillers available from chemists without a prescription and used to treat tension headaches and migraines can cause this problem. These include:

  • codeine
  • paracetamol
  • anti-inflammatory painkillers such as aspirin and ibuprofen 
  • a group of specific anti-migraine medicines known as triptans, such as sumatriptan

Some painkillers are more likely to cause medication-overuse headaches than others.

“Painkillers containing codeine are most likely to lead to overuse headaches,” says Dr Ahmed. His advice to prevent painkiller headaches is:

  • Don't take painkillers for headaches on more than two days in each week.
  • Don’t take painkillers for headaches for two or more consecutive days.
  • Completely avoid taking codeine or codeine-containing painkillers such as Syndol and Solpadeine.

Treating painkiller headaches

The treatment for medication-overuse headaches is simple - stop taking painkillers.

According to Dr Ahmed, if you've been dependent on painkillers for months rather than years, the best approach is to stop abruptly. “Your headaches will probably get worse immediately after stopping, and you may feel sick or sleep badly, but after seven to 10 days when the painkillers are out of your system you'll feel better,” he says.

If you’ve been getting painkiller headaches for several years as a result of taking codeine-containing products, it can be dangerous to stop abruptly. You'll need gradually to reduce the number of painkillers you take, and this is best done under the supervision of a doctor.

The future

Once your painkiller headaches have stopped and your tension headaches or migraines are back to normal, you can start to use painkillers again as you need them.

“Around 70-80% of people with medication-overuse headaches manage to stop regularly taking painkillers and feel much better as a result. The other 20-30% relapse over time and may have to go through withdrawal periods repeatedly,” says Dr Ahmed.

Common Q and As

Read answers to the common questions that people have about painkillers and other medicines, including 'Can I take paracetamol if I'm on antibiotics?' and 'Can I drink alcohol if I'm taking painkillers?'.

Last reviewed: 08/06/2011

Next review due: 08/06/2013

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