Pelvic inflammatory disease

Introduction 

Pelvic inflammatory disease (PID) is a bacterial infection of the female upper genital tract, including the womb, fallopian tubes and ovaries.

Most cases of PID are caused by an infection in the vagina or the neck of the womb (cervix) that has then spread to the reproductive organs higher up.

Many different types of bacteria can cause PID, but most cases result from a chlamydia or gonorrhoea infection (see Causes for more information).

What happens

When infection spreads upwards from the cervix, it causes one or more of the following:

  • endometritis - inflammation and infection of the endometrium (womb lining),
  • salpingitis - inflammation and infection of the fallopian tubes,
  • parametritis - inflammation and infection of the tissue around the womb,
  • oophoritis - inflammation and infection of the ovaries,
  • an abscess (pocket of infected fluid) in the ovary and fallopian tube, and
  • pelvic peritonitis - inflammation and infection of the peritoneum (lining of the inside of the abdomen).

If you develop salpingitis, the lining of the fallopian tubes swells and the already narrow canals become even narrower. This means fertilised eggs may not be able to move along normally, increasing the risk of ectopic pregnancy (a pregnancy that occurs outside of the womb) and infertility - see Complications for more information.

Who is affected

PID most commonly develops in sexually active women who are aged between 15 and 24 years.

The disease is fairly common: it is the reason for one in 60 visits to a GP by a woman aged under 45. There are many more women with PID who experience few or no symptoms.

Outlook

If diagnosed at an early stage, PID can be treated quickly and efficiently with antibiotics. However, if left untreated, it can lead to more serious long-term complications such as an ectopic pregnancy.

Further infection is common. After a first episode of PID, one in five women has more episodes, mostly within two years. Repeated episodes of PID are associated with an increased risk of infertility.

Last reviewed: 28/01/2010

Next review due: 28/01/2012

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