Urticaria (hives) - Complications 

Complications of urticaria 

Angioedema

Around half of people with chronic (persistent) urticaria and a quarter of people with acute (short-term) urticaria also get a related condition called angioedema.

Angioedema is swelling in the deeper layers of the skin, usually in the eyelids, lips and sometimes the mouth, although it can occur anywhere.

The swelling is often severe and is caused by a build-up of fluid. The symptoms of angioedema can affect any part of the body, but they usually affect the:

  • eyes
  • lips
  • genitals
  • hands
  • feet

The swelling often appears suddenly, and is much more severe than normal hives (nettle rash). It usually lasts for one to three days.

As well as visible swellings, angioedema can cause some or all of the following symptoms:

  • a burning hot or painful feeling in the swollen areas
  • swelling of the inside of the throat, the air tubes in the lungs and the tongue, making breathing difficult.
  • swelling of the transparent layer of cells that cover the white part of the eye (the conjunctiva), which affects vision

Medication, such as antihistamines and steroid tablets (oral corticosteroids) can be used to relieve the swelling.

Steroid injections may be needed for more severe cases of angioedema, where a person has breathing difficulties. These are usually administered in hospitals or specialist clinics by an allergy or immune system specialist.

Read about the treatment of angioedema.

Emotional impact of chronic urticaria

Living with any long-term condition can sometimes be upsetting. For many people, chronic urticaria can have a considerable negative impact on their quality of life and mood.

Having to live with itchy skin can be particularly upsetting.

One study found that the condition can have the same negative impact as heart disease.

The same study found that one in seven people with chronic urticaria had some sort of psychological or emotional problem, such as stress, anxiety or depression.

Contact your GP if your urticaria is getting you down. Effective treatments are available to help improve symptoms of stressanxiety and depression.

Talking to friends and family can also help improve feelings of isolation and help you cope better with your condition.

Read about how talking to others can help.

Last reviewed: 01/05/2012

Next review due: 01/05/2014

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Comments are personal views. Any information they give has not been checked and may not be accurate.

Itchymcscratchy said on 18 February 2013

I have had chronic urticaria for 26 years, it started when I was 17, no one knew how to treat it and I was constantly told it was idiopathic which didn't help as I still wanted a cure for what I think is a very debilitating disease, eyes and lips swell, skin covered in a horrible angry rash, joint pain, feeling cold and shivery when you're warm to the touch, horrendous thing. I have tried Chinese medicines, diet control (even though they knew I was not allergic to anything) private medial appts, it was diagnosed as auto-immune urticaria and was treated as such then it was decided it was stress/emotion related and suggested I try Cognitive Behavioural Therapy which I have just finished, it was very worthwhile and made me re-examine the reasons why I react to certain situations, thus reducing my stress. I still take 2 anti-histamine tablets per day, hoping to cut that down to 1 but I feel I still need them. I feel like urticaria is just brushed aside because Medics don't really know how to treat it but like the man in the previous post I have been at the end of my tether sometimes, sitting up in bed at 2am crying and feeling like there are things crawling all over you, scratching until your skin bleeds, all while trying to hold down a full-time job. it's sadly a very neglected area of medicine which makes it tougher to explain to others which is why it's often referred to by me as 'that aul rash'

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Mugflump said on 27 January 2013

I suffered this for about 18 months ,chronic urticaria ,it started from my legs and worked its way up my body ,with my head being last ,I had this on every part of my body ,my head would swell half the size more than it is normally ,my lips would swell to an unbelievable size,never thought your body could do this ,also my throat would swell ,my hole body felt like it was on fire this drove me nearer to the edge ,if I could of took my skin off I would have ,I had never herd of it before until I had it ,and know one I know had herd of it ,I do feel it is still there from time to time ,as I do right now and this is six years on from when I first got it ,I think mine is caused by stress ,as back when I had it before I was under a lot of stress ,and the same applies now ,I'm not sure if you can get it again ,but I'm sure it is lurking under my skin waiting to break out ,I am a healthy man and very active ,and this by far is the worst thing that has ever been wrong with me ,I have only ever met one other person with urticaria ,and he was a three year old boy who was walking past me with his mother ,so I stopped them and said to the mother has your boy got urticaria ,she was shocked that I knew what it was ,if you have suffered with it ,you know ,at times I was suicide with it ,I had so many pills to combat it ,and after 18months it went

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