MRSA infection - Causes 

Causes of MRSA infection 

MRSA is caused by strains of bacteria that have developed resistance to a number of widely used antibiotics.

How MRSA spreads

MRSA bacteria are usually spread through skin-to-skin contact with someone who has an MRSA infection or who is colonised by the bacteria. Colonised means bacteria are present on your body but do not cause any symptoms.

The bacteria can also spread through contact with towels, sheets, clothes, dressings or other objects that have been used by a person who is infected with or colonised by MRSA.

MRSA can survive for long periods on objects or surfaces, such as door handles, sinks, floors and cleaning equipment.

Healthcare-associated MRSA (HA-MRSA)

It is much more common for someone to develop MRSA while they are in hospital or a care home than in the community. This is because:

  • People in hospital often have a point that allows bacteria to enter their body, such as a surgical wound, burn, catheter (a tube used to drain away urine) or an intravenous tube. If a patient who is colonised with MRSA bacteria touches their wound or catheter tube, they may infect themselves.
  • People in hospital tend to be older and have more complex health problems than the general population, which makes them more vulnerable to infection.
  • People in hospital are surrounded by a large number of people, both patients and staff. This makes it is easier for bacteria to spread from person to person, or from a person to an object and then to another person.

Who is at risk?

Factors that increase your chance of developing HA-MRSA include:

  • a weakened immune system, for example in elderly people, newborn babies and people with a long-term health condition, such as type 2 diabetes
  • an open wound
  • a catheter or an intravenous drip
  • a burn or cut on the skin
  • a severe skin condition, such as a leg ulcer or psoriasis
  • surgery
  • taking frequent courses of antibiotics

MRSA infections usually develop in people being treated in hospital, particularly patients in intensive care units (ICUs) and on surgical wards.

Community-associated MRSA

MRSA contracted outside hospitals is known as community-associated MRSA (CA-MRSA). It's much less common than HA-MRSA.  

However, in recent years the number of cases has increased and could continue to increase in the future. The following factors increase your risk of getting CA-MRSA:

  • living in a very crowded environment - for example a military base, prison or student hall of residence
  • frequent skin-to-skin contact - outbreaks of CA-MRSA have been reported in people who play contact sports, such as rugby
  • cut or grazed skin - this is more vulnerable to infection, as are people who regularly inject illegal drugs, such as heroin
  • contaminated items and surfaces - places where many people share utensils, tools or where many people are likely to touch the same surfaces
  • lack of cleanliness - outbreaks of MRSA can occur in homeless people or in people on active military duty who have limited access to cleaning facilities
  • previous use of antibiotics
  • show glossary terms
Antibiotics
Antibiotics are medicines that can be used to treat infections caused by micro-organisms, usually bacteria or fungi. Examples include amoxicillin, streptomycin and erythromycin.
Bacteria
Bacteria are tiny, single-celled organisms that live in the body. Some can cause illness and disease and others are good for you.
Catheter
A catheter is a thin, hollow tube usually made of rubber that is placed into the bladder to inject or remove fluid.
Drip
A drip is used to pass fluid or blood into your bloodstream, through a plastic tube and needle that goes into one of your arteries or veins.
Immune system
The immune system is the body's defence system, which helps protect it from disease, bacteria and viruses.
Intravenous
Intravenous (IV) means the injection of blood, drugs or fluids into the bloodstream through a vein.
Ulcer
An ulcer is a sore break in the skin, or on the inside lining of the body.

Last reviewed: 23/09/2011

Next review due: 23/09/2013

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