Hidradenitis suppurativa 

  • Overview


Lifestyle tips for people with HS

  • lose any excess weight
  • stop smoking, if you smoke
  • manage stress, as this can worsen your symptoms
  • use an antiseptic skin wash or antiseptic soap  this may be prescribed alongside other treatment
  • hold a warmed flannel to the spots to encourage the pus to drain
  • wear loose-fitting clothes
  • avoid shaving the skin and wearing perfume or perfumed deodorants in the affected areas

Many people with HS benefit from joining a local support group – ask your doctor for details of your nearest one, or contact The Hidradenitis Suppurativa Trust.

Hidradenitis suppurativa (sometimes known as acne inversa) is a painful, long-term skin disease that causes abscesses and scarring on the skin – usually around the groin, buttocks, breasts and armpits.

It's not known exactly what causes hidradenitis suppurativa (HS), but the disease is linked to inflamed sweat glands and plugging of the hair follicles.

An estimated 1% of the population has HS – but this may be an underestimate, as some people might be too embarrassed to seek diagnosis and treatment.

What are the symptoms?

HS ranges from mild to severe.

It causes a mixture of red boil-like lumps, blackheads, cysts, scarring and channels in the skin that leak pus. These lumps and spots are found around the groin and armpits, and sometimes under the breasts and in other areas (see below). 

HS may sometimes be mistaken for acne, folliculitis (inflammation of the hair follicles) or a sexually transmitted infection (STI), such as herpes.

Some of the lumps may become infected with bacteria, causing a secondary infection that will require antibiotics to treat. HS is very painful.

The disease tends to start with a firm pea-sized lesion developing in one place. This either goes away on its own or ruptures after a few hours or days, to ooze pus.

Often, new lumps will soon appear in an area nearby. If these are not controlled with medication, larger lumps may form and spread. Narrow channels also form under the skin that break out on the surface and leak pus. These are called sinus tracts.

HS is a lifelong, recurring condition that requires constant management (see the Outlook section below).

Stages of the disease

Doctors classify the disease into three distinct stages:

  • Stage 1 – single or a few isolated abscesses without scarring or sinus tracts.
  • Stage 2 – recurrent abscesses in more than one area and the beginning of the formation of sinus tracts.
  • Stage 3 – widespread abscesses with many interconnected sinus tracts under the skin. There may be severe scarring and continuous leaking.

Main affected areas

HS usually affects skin in the following areas:

  • around the groin and genitals
  • in the armpits
  • around the bottom (anus)
  • on the buttocks and inner thighs
  • below the breasts

The abscesses may spread to the nape of the neck, waistband and inner thighs. Other isolated areas have been known, including the front or back of the legs, the sides, the back area and even the face.

Many people with HS develop a pilonidal sinus, which is a small hole or "tunnel" in the skin, usually at the top of the buttocks, where the buttocks separate. 

What are the causes?

The exact cause of HS is unclear, but the bumps and spots appear to be the result of blocked sweat glands and hair follicles.

However, the disease is not infectious and is not linked to poor hygiene.

It is thought that HS may be caused by a problem with the immune system. According to the British Association of Dermatologists, it may be linked to Crohn's disease. Many HS patients also suffer from another underlying autoimmune disorder (where the immune system attacks the body's own cells and tissues).

Who is affected?

HS usually starts around the age of puberty, but it can appear at any age.

It is less common for HS to occur before puberty or after the menopause, leading some experts to believe that the sex hormones have some sort of influence on the disease.

In around a third of cases, HS runs in families.

HS also affects more women than men, for reasons that are unclear.

Many people with HS:

  • are smokers
  • are overweight
  • also have hirsutism (excessive hair growth) and/or acne, both of which are linked to levels of sex hormones 

Smoking and being obese are likely to make the condition worse.

How is it treated?

HS can be difficult to manage and there is no cure. The aim is to catch the disease in its early stages and prevent it getting worse. Therefore, an early diagnosis is important.

In the early stages, the disease may be controlled with medication. Persistent and severe cases may require surgery. These treatments are outlined below.


If your lumps are particularly painful, red and oozing pus, your GP or specialist may prescribe a two-week course of antibiotic tablets, as there may be a secondary infection present.

If there is no suspected bacterial infection, antibiotics are used as suppressive treatment. This involves a course of antibiotics, usually lasting up to three months, with the aim of remission (a symptom-free period).

You may be prescribed a topical antibiotic cream, such as clindamycin 1%, to use twice daily. Oral antibiotics include erythromycin, tetracycline, lymecycline, doxycycline or clindamycin, alongside a number of other options.


Antiseptic washes such as 4% chlorhexidine wash are frequently prescribed alongside other treatments.

Antiseptics are usually applied all over the body, except the head and neck, then washed off after a few minutes.


Retinoids are vitamin-A based drugs such as isotretinoin. They are not as effective for treating HS as they are for acne, but a course for 6 to 12 months may help to control some of the spots and lumps.

Isotretinoin should be used with caution, with the advice of a specialist. It cannot be taken during pregnancy, and possible side effects include dry lips, skin and eyes. 

Read more about the side effects of isotretinoin.

Contraceptive pill

Women whose HS flares up before their period may benefit from taking the contraceptive pill for 12 months or more.

The pill contains an artificial version of oestrogen, which should help reduce secretions from the sweat glands and control the lumps.

Immunosuppressive treatments

Severe cases of HS may require treatments that suppress the immune system, such as corticosteroids, ciclosporin and biological drugs.


You may be prescribed steroid medicine (corticosteroids) such as prednisolone to reduce severely inflamed skin. Corticosteroids can be taken as tablets, or you may have an injection of the drug directly into your affected skin.

Possible side effects of corticosteroids are fluid retention, weight gain, constipation and mood swings. 

Find out more about the side effects of corticosteroids.


Ciclosporin is a powerful medication that suppresses the immune system. For some patients with HS, it can relieve symptoms for a few months.

However, this medicine can cause vomiting, diarrhoea, high blood pressure, numbness, and kidney and liver problems. 

Learn more about the side effects of ciclosporin.

Infliximab and adalimumab

Biological drugs like infliximab or adalimumab, which also suppress the immune system, may be prescribed for severe cases of HS. Your dermatologist will usually only prescribe them if other treatments don't work.

Infliximab and adalimumab are given by injection at a hospital or clinic. You may need to have the injections at regular intervals.

Possible side effects include blood disorders, infection and cancer of an organ. Speak to your doctor about these side effects if you are considering taking this medication.


A surgical procedure may be considered if your HS is not controlled with medication, or suddenly becomes worse.

If you have some very large lumps that will not clear with antibiotics, you may be offered one of the following treatments:

  • incision and drainage or removal – cutting off the lids of the lumps, and draining or scraping out the contents inside, or removing the lumps altogether
  • laser ablation – using a laser to remove the lumps (this has no proven benefit and is an experimental treatment)
  • cryotherapy – freezing off the lumps with liquid nitrogen


HS persists for many years and there is no cure, but symptoms may be improved with treatment if it is diagnosed early.

Not all people with HS progress to stage 3 – the disease can be controlled so it doesn't progress beyond stage 1.

However, HS can affect your life in many ways. Routinely changing dressings and living with the pain, discomfort and embarrassment of the symptoms can affect quality of life and lead to stress, anxiety and depression.

If you are having problems coping, speak to your health professional or a charity to see what support is available. 

Read about how to find mental health support.

Page last reviewed: 05/10/2014

Next review due: 05/10/2016


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The 8 comments posted are personal views. Any information they give has not been checked and may not be accurate.

Karen L R said on 07 November 2014

I have HS Stage 3 around the groin and upper thigh and I am frequently researching the disease and treatments and I came across the following article: www.bmj.com/content/346/bmj.f2121

I took this finding to my GP and, just four weeks into the recommended ten week course now, I am experiencing significant improvements. Suppuration and pain stopped a week ago and all 'lumps' have reduced in size and softened. My quality of life is improving immensely.

Three retrospective studies totalling 118 patients, showed significant improvement in 81% of patients at week 10 and a response across all grades of HS. No long term follow-up data is available but I will keep you posted as to my progression here.

These drugs do carry some risk and my liver is being checked every four weeks whilst on the drugs, however, your health professional will advise accordingly.

Although it is early days for myself in terms of this treatment, it is proving effective for me and for the first time in years I am actually considering a beach/pool holiday.

Good luck to all should you wish to try this method.

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CheGordoJo said on 04 November 2014

I've had the condition since I was 17 which is 9 years now. It is mainly concentrated to my armpits though I do get the odd lump in my groin. I had an operation to remove one lump in my right armpit 7 years ago and until middle of this year had been HS free in the right armpit. This year I have developed a hard to shift infection but being the first in 7 years I am not overly troubled by it. The left armpit however has been a nightmare for the last 7 years. Constant lumps, infection, leaking and bleeding. I've ruined so many clothes over the years and never go out in just a vest top without a small jacket. Having said all this just yesterday I have had all of the hair-bearing skin removed from my armpit. It was a bigger operation but my consultant believed I needed it & I really hope this sorts me for life. One can but be positive! The best thing to do is speak up as early as possible. Before it gets to the point of no return. Sorry for the ramble, hope this will help somebody.

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RuthieHerts said on 19 October 2014

I was interested to see the comment in the "official" blurb that many people with this condition are overweight - possibly because the condition is linked to Insulin resistance, which if un-checked will cause weight gain. I had this condition from teenage years despite being within the "normal" weight range with a BMI of 23.9. The condition continued until I was diagnosed with ancanthosis negricans and PCOS, all too a result of the insulin resistance, and I was treated with Metformin. Good luck.

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Philip61 said on 29 August 2014

Hi everyone after reading the views and comments left on this forum on ( hs) I would like to share some of my experiences with you ? I contracted this illness approx 25 yrs ago and since then after many many different coarses of antibiotics,operations, and and endless tablets I'm now so mixed up with these medicines I'm now on antidepressants as I can't cope with all the trips back and forward to hospital all the time thinking there's a cure out there but alas no! I'm now taking a oral tablet ( dapsone) but after 3 months don't think I'm going anywhere with this either but if you ain't had any type of depression in your lifetime I would recommend ( but very carefully) reacutan tablet sorry not correct spelling as in the short time I did manage to take this medicine IT DID WORK but like everything else it has it's complications (GOOD LUCK) to all

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traybo35 said on 19 July 2014

User885803,I read with interest your comments on Hidradenitis Suppurativa,of which I have painfully suffered from for years,I have tried dozens of remedies and Antibiotics some antibiotics I was taking for 12 months to no avail,as there is no cure for this vile illness I am pretty much open to trying anything,after just having to have the past week off work due to this illness I'd be greatful if you could share with me the benefit of Turmeric and how you apply or take this,regards.

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User885803 said on 06 July 2014

Turmeric worked for me with Hidradenitis Suppurativa (HS.) I suddenly got HS in 2008 (aged about 27,) I had it in my armpits, and before taking turmeric I had an HS lump cut out of my armpit and analysed and was diagnosed with HS. I was prescribed anti-biotics, which did nothing to help apart from giving me nasty side effects. I think I also tried washing the area with anti-bacterial wash to no avail.

My mum researched HS on the net and found out about turmeric. Since 2008/09 I have been taking turmeric daily and the HS has never come back. This stuff is truly amazing and now I am fascinated by the benefits it has. It has been used for cooking (curries) and medicinal reasons in Indian and Asian cultures for a vey long time. It is a shame that it hasn't been researched and tested by a reputable company or organisation but this must be because no pharmaceutical company will care as they wouldn't be able to profit off a herb!

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Marbella1 said on 21 May 2014

I have stage 3 hd and am in constant pain . I have tried all treatments I am not over weight I do not smoke and I eat healthily . I have had all operations for this disease and laser hair treatment. Vitamin injections nothing cures this please if you have stage 3 like myself do not buy into these miracle treatments advertised on the internet they do not work I wasted a fortune on most of these I live in constant pain with this terrible illness and would like doctors to take it much more seriously as this is needed in order to find a cure as of course highlighting this illness will then hopefully raise awareness and funding.

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madz2020 said on 06 February 2014

I had foliculitis and small hidradenitis bumps on my pubic area, they started to appear at puberty and got steadily more frequent. I recently started laser hair removal therapy and it has changed my life. I'm looking forward to a summer where I can wear bikini bottoms which I have never felt comfortable enough to do before. I have so much more confidence with my boyfriend. And im just glad that I had the laser done before I got any serious scars. I recommend it to anyone who thinks they might have hidradenitis superateva, can't sing its prases enough.

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Hirsutism is when a woman has excessive hair growth. Hirsutism is caused by an excess amount of male sex hormones.