Thyroid, overactive 

Introduction 

Overactive thyroid gland

An endocrinologist explains what causes an overactive thyroid gland, leading to over-production of thyroid hormones, and the variety of treatment options.

Overactive thyroid, also known as hyperthyroidism or thyrotoxicosis, is a condition that occurs when there is too much thyroid hormone in the body. The condition is more common in women than men.

The role of the thyroid gland

The thyroid gland is found in the neck. It produces hormones that are released into the bloodstream to control the body's growth and metabolism. These hormones are called thyroxine and triiodothyronine. They affect processes such as heart rate and body temperature, and help convert food into energy to keep the body going.

Normally, the levels of thyroxine and triiodothyronine in the blood are carefully controlled so that these processes happen at a stable rate.

However, in hyperthyroidism, the thyroid gland produces an excess amount of thyroxine or triiodothyronine, which speeds up the body's metabolism. This causes symptoms such as:

  • hyperactivity
  • an increased appetite
  • sudden weight loss or gain

See Overactive thyroid - symptoms for more information

Overt and subclinical hyperthyroidism

There are several causes of an overactive thyroid gland. The most common is Graves' disease, in which the body's immune system targets the thyroid gland and causes it to produce too much thyroid hormone.

Once diagnosed, overactive thyroid can be classed as either:

  • overt, which means that it causes symptoms
  • subclinical, when the levels of thyroid hormone are still within normal limits

Outlook

Overactive thyroid can be effectively treated using medicines to slow the production of hormones from the thyroid gland, as well as radiotherapy and in some cases surgery. For more information, see Overactive thyroid - treatment.

However, if it is not successfully controlled, overactive thyroid can cause other health problems such as irregular heart rhythms and osteoporosis (weak, brittle bones).

If it is not treated, overactive thyroid can be fatal.

Last reviewed: 10/05/2010

Next review due: 10/05/2012

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Comments are personal views. Any information they give has not been checked and may not be accurate.

dUb Samurai said on 06 February 2012

Hi I am a 19 year old male and have been severly underweight my whole life. I weigh 8 and a half stone which is less than I weighed 5 years ago. I'm always eating, have very irregular sleep and have pretty much no muscle. I feel tired all the time and get really anxious for no reason. My heart is always going a mile a minute whatever I'm doing and have horrible anxiety. I haven't been to the doctor's but was wondering how this compared to other people's experiences with this disorder.

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smergyl said on 10 August 2011

I have been recently diagnosed with an overactive thyroid and have been given carbimazole and bisoprolol to regulate it. Sadly in the past an ignorant doctor has not seen the signs and has diagnosed me with the eating disorder Anorexia. I now have to take my husband with me to doctors appointments so he can verify I do eat quite a bit and am not starving myself. I eat around 2500 cals a day and still have a bmi of 16, it has stayed steady for some time and doesn't fluctuated that much. I am hoping the tablets will fix this as I'm sick of the way I get treated when I go to the docs for something and get tons of abuse for my weight.

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angeleyes06 said on 20 October 2010

i found a lump in my neck and went to see my doctor who then reffered me for blood tests and scans. i had a complete thyroidectomy in september 2009 and im now on 175mg thyroxine and i feel so much better, no more palpatations or anxiety attacks. i also have bloodtests done every 3 months. if you feel the symptoms returning yourself you can request a bloodtest to have your levels checked.

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Taylor1980 said on 29 September 2010

My symptoms started when I was 15. Lost loads of weight whilst eating like a horse. It was my optician who diagnosed it as he noticed my eye's starting to bulge. I was sent to the hospital and diagnosed with overactive thyroid and thyroid eye disease. I was on carbimizole for ages but it did nothing. I had 90% of my thyroid removed aged 16, which then left me underactive and on thyroxine for the rest of my life.Had radiotherapy to try and shrink my eye musle but that didn't work. I had eye surgery aged 18 to remove some of the bone from my eye sockets, which sorted them out at last (except for another surgery to correct my eye musles). Since then I have been well controlled on 200mg of thyroxine daily. I did get type 1 diabetes when I was 18, but I'm not sure if this is linked to my thyroid problems. I had my first child in 2007, 5 weeks early, 5lb 6oz , and had to stay in hosp for 12 days as he had a few problems, but is now a normal, happy 3 year old. My medics have been great considering, my doctor has told me I'm her only patient with this condition. This week however I have been having problems with my heart racing and generally feeling tired. Awaiting my blood test results but my doctor thinks it may have gone overactive again, even though I only have 10% left. Has anyone else had a reaccurance like this?

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ashley gordon said on 11 September 2010

Hi im 13 years old and i went to my GP because i couldnt lose any weight and just kept gaining it and i can sleep all day and night if i could. My family thought there was something wrong with me as i just gained weight and couldnt lose it.
I hated been like this so i went to my doctor and had my blood taken.
Then my mam got a phone call from my doctor saying my blood tests had came back, so we went down and got referred to hospital staight away with a very bad under active thyroid. They took my blood and done what they had to do and after a while gave me some tablets.
Im on 75mg at the minute but i wish the doctors would just put me up faster its taking ages and im not on my steady amount as i need to be put on a high amount.
I have lost a bit of weight as i go to the gym. But other then that i havnt changed a bit.
but hopefully i will when im on my full amount .
I CANT WAIT.....

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bigthroat80 said on 17 August 2010

I went to my gp with a goitre and feeling rough. GP referred me straight away. Saw a consultant within 3 weeks. Diagnosed with graves. All the medical professional have been great. And more importantly made me feel better.

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molden said on 31 July 2010

it is seven and a half years since i started with symptoms.one and a half years were spent spent telling a so called doctor of these symtoms. they just kept nodding like a noddey dog and smiling.By chance went to another doctor and was diagnoised right away.I have just lived through the worst seven and a half years of my life all because a doctor who is being paid a lot of tax payers money can not do the job they are being paid to do. I have had one eye opperation and will have to have another. Why are so many so called doctors allowed to get away with not being competent. They are costing the NHS a fortune.I think it is about time we charged them their mistakes then we would start getting a decent standard of doctors in our health centers and cut down on the so called waste in the NHS.

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sirmdolan said on 23 July 2010

i have had symptoms for well over four months and initially thought i had throat cancer so i was extremely concerned about my condition i saw one doctor who basically fobbed me off as though i was some sort of hypochondriac and sent me away i saw a different doctor on the second occasion who i was equally unimpressed with although he did make me an appointment to see an ENT specialist which i attended only to be sent home again by a professional who was also flummoxed and could shed no light on my condition!, During this time it came to light to my doctors receptionist that i had moved house and was no longer in the catchment area so i was to to find another doctors practice ASAP as they would no longer see me any more. I promptly to their advice and found myself a new practice on monday this week 19/7/2010 i went to see my new doctor with the same symptoms blood was taken and i was sent to the hospital for an x-ray, on tuesday i received a phone call from the doctors receptionist asking me to make an appointment as my blood test results were back and the doctor wished to discuss them with me , on wednesday i returned to the doctor and was informed that i had an over-active thyroid .

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Sickly said on 23 June 2010

The first comment sounds very much like my own experience. In my case the GP did find a large nodule on my thyroid, it was scanned and rescanned, beyond that nothing.

I have now identified for myself symptoms over over production of thyroxine.

I plan to see the GP again - but will they do anything ?

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Pedros143 said on 19 April 2010

Thyroid GP treatment seems to be a case of " identify and forget", (identifying usually done by the patient.) There appears no real follow up or concern on having regular blood tests or symptom checking for the patient once this is confirmed. Very little information is given to the patient about the downside of levothryoxine, so any after effects come as a surprise only to the patient, who then has to make another appointment to find out about them. Pretty poor show all round on this specific disease management.

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User80252 said on 26 March 2010

i had a subtotal thyroidectomy in 1990 for an hyperthroidyism and was not given any medication. Over the past few years i have felt symptoms return.

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