High cholesterol 

Introduction 

Preventing and reducing high cholesterol

Too much cholesterol in the body causes coronary diseases such as angina, heart attack and stroke. Dr Jonathan Morrell explains who is at risk and the treatments that are available.

Lower your cholesterol

A fatty diet can raise your cholesterol, increasing your risk of heart disease and stroke. Get food tips for lowering your cholesterol

Cholesterol is a fatty substance known as a lipid and is vital for the normal functioning of the body. It is mainly made by the liver but can also be found in some foods we eat.

Having an excessively high level of lipids in your blood (hyperlipidemia) can have an effect on your health. High cholesterol itself does not cause any symptoms, but it increases your risk of serious health conditions.

About cholesterol

Cholesterol is carried in your blood by proteins, and when the two combine they are called lipoproteins. There are harmful and protective lipoproteins known as LDL and HDL, or bad and good cholesterol.

  • Low-density lipoprotein (LDL): LDL carries cholesterol from your liver to the cells that need it. If there is too much cholesterol for the cells to use, it can build up in the artery walls, leading to disease of the arteries. For this reason, LDL cholesterol is known as "bad cholesterol".
  • High-density lipoprotein (HDL): HDL carries cholesterol away from the cells and back to the liver, where it is either broken down or passed out of the body as a waste product. For this reason, it is referred to as "good cholesterol" and higher levels are better.

The amount of cholesterol in the blood (both LDL and HDL) can be measured with a blood test. The recommended cholesterol levels in the blood vary between healthy adults and those at higher risk. 

Why should I lower my cholesterol?

Evidence strongly indicates that high cholesterol can increase the risk of:

This is because cholesterol can build up in the artery wall, restricting the flow of blood to your heart, brain and the rest of your body. It also increases the chance of a blood clot developing somewhere.

Your risk of coronary heart disease (when your heart's blood supply is blocked or disrupted) also rises as your blood's cholesterol level increases and this can cause angina during physical activity.

What causes high cholesterol?

There are many factors that can increase your chance of having heart problems or stroke if you have high cholesterol, including the following:

  • an unhealthy diet: some foods already contain cholesterol (known as dietary cholesterol) but it is the amount of saturated fat in your diet which is more important
  • smoking: a chemical found in cigarettes called acrolein stops HDL from transporting LDL to the liver, leading to narrowing of the arteries (atherosclerosis)
  • having diabetes or high blood pressure (hypertension)
  • having a family history of stroke or heart disease

There is also an inherited condition known as familial hypercholesterolaemia (FH). This can cause high cholesterol even in someone who eats healthily.

Read more about the causes of high cholesterol.

When should I test my cholesterol levels?

Your GP may recommend that you have your blood cholesterol levels tested if you:

  • have been diagnosed with coronary heart disease, stroke or mini-stroke (TIA) or peripheral arterial disease (PAD)
  • are over 40
  • have a family history of early cardiovascular disease
  • have a close family member has a cholesterol-related condition
  • are overweight
  • have high blood pressure, diabetes or a health condition that can increase cholesterol levels, such as an underactive thyroid

Read more about how high cholesterol is tested.

How can I lower my cholesterol levels?

The first step in reducing cholesterol is to maintain a healthy, balanced diet. It is important to keep your diet low in fatty food, especially food containing saturated fat, and eat lots of fruit, vegetables and wholegrain cereals. This will also help to prevent high cholesterol from returning.

Other lifestyle changes can also make a big difference. It will help to lower your cholesterol if you do regular exercise and quit smoking. Read more information about how to stop smoking and tips on improving your health and fitness.

If these measures are not helping to reduce your cholesterol and you continue to be at a high risk of heart disease, your GP may prescribe a cholesterol-lowering medication such as statins. Your GP will take into account the risk of any side effects from statins and the benefit of lowering your cholesterol must outweigh any risks.

Read more about how high cholesterol is treated.

Last reviewed: 15/11/2011

Next review due: 15/11/2013

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Comments are personal views. Any information they give has not been checked and may not be accurate.

mark40odd said on 09 December 2012

y ddraig coch, good to see you are keeping fit, that should help your HDL numbers. My parents have slightly high cholesterol too (although not as bad as yours) and I have been overweight and unfit recently so I am looking into this problem myself.
I wouldn't go too far towards a veggie diet, meat and especially fish are important parts of the diet for health. (and eggs too) Try to eat oily fish regularly (or if not, take a fish oil supplement), that might help lower your triglycerides. You could try reducing your bread and sugar intake as well and see if that helps your numbers - I believe it may.

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y ddraig coch said on 24 January 2012

I am 65, female and fitter than most 16year olds. However I did have a cholesterol level of 7.6. A genetic condition. My GP agreed that it would be very difficult to improve my diet or my lifestyle. (I Recently walked up mountains for 9 miles on Lanzarote)

One statin caused very painful joints. The next was a slightly more expensive version and caused palpitations.

The last GP I saw insisted I stay on the statin because he is not concerned about now but the next 30 years! and would do liver function tests on my next visit. I do not think so.

I would happily live for another 30 years providing I have all my faculties and a reasonable quality of life.

I am now attempting to control the levels by adopting an almost vegetarian diet and fish and occasional meat.

I too despair of the NHS having given it almost 50 years of my working life, paid towards my pension etc. etc.. I refuse to go privately for any health treatment. The NHS should be run by health professionals i.e. doctors, nurses and experts in health management. PFI's were the worst thing ever for the National Health Service.

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Pravda said on 21 December 2011

If I fall over and graze my knee then a protective clot will form over the subsequent inflammation of the damaged skin. In order to hold the blood platelets together then the body deploys a substance called fibrin so forming "plaque like" scab over the wound. Cholesterol then gets on and repairs the damaged skin.

So if you analysed thousands and thousands of scabs from peoples knees what would you logically conclude.

Fibrin (and cholesterol) is highly associated with scabs.

Therefore grazed knees are caused by..............

If you are a Doctor or Pharmaceutical drug pusher (Think about it !) then the answer is obvious.

Coincidently it is a medical fact (feel free to check) that 50% of all heart attack victims have normal cholesterol levels and NO prior symptoms.

How about this for a good idea in these cash strapped times. Reduce the number of ambulance crew so as to cut the number of road traffic accidents. After all they are highly associated with them.

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PRL said on 27 November 2011

To be exact cholesterol is both an alcohol - it has an OH attached to an aliphatic carbon - and a fatty substance - as the molecule is predominantly non-polar.

Fairly clear article. Might be nice to know about OK ratio of LDL /HDL

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LindaJW said on 20 May 2011

Cholesterol is not an alcohol.

Cholesterol is a sterol (a combination steroid and alcohol) and a lipid found in the cell membranes of all body tissues, and transported in the blood plasma of all animals. Lesser amounts of cholesterol are also found in plant membranes.

Triglycerides come from the food we eat as well as from being produced by the body.Triglycerides are chemical compounds digested by the body to provide it with the energy for metabolism. Triglycerides are the most common form of fat that we digest, and are the main ingredient in vegetable oils and animal fats.

The triglyceride molecule is a form of the chemical glycerol (tri=three molecules of fatty acid + glyceride=glycerol) that contains three fatty acids. To be absorbed, these parts are broken apart in the small intestine, and afterwards are reassembled with cholesterol to form chylomicrons. This is the source of energy for cells in the body. Fat cells and liver cells are used as storage sites and release chylomicrons when the body needs the energy.
Excess carbohydrate consumption and sugar spikes caused by carbohydrate consumption lead to the formation of triglycerides.
Triglycerides
Triglycerides, a type of lipid found in your blood, form when your body converts calories it does not want into fat for storage. When you body needs energy, it can use these triglycerides.

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User363 said on 19 November 2010

Thanks for all your comments. These pages will be fully reviewed in October 2011.

I can confirm that the patient information we have provided on these pages is clinically accurate.

Regards,
The Editor, Health A-Z

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Brother Francis said on 06 November 2010

Please can this page be reviewed promptly? Its next scheduled review is nearly a year away.

rodders995 made a comment, Hepsi8 supported it but koebner disagreed strongly. I have a view as to which is correct but I am not medically qualified so I will not express it; that won’t help. However someone with the proper knowledge needs to review and resolve this. I expect there will always be medical debate but surely cholesterol is understood better than the debate on this page suggests. If there is a level of uncertainty the page should express it openly. If there is no uncertainty the page should be definitive.

As for me, I could do with more information.

I was recently diagnosed as having a raised cholesterol level but below the level that would normally be treated medically, but I wanted to know more. The page gives the government’s recommended maximum level but then says the *average* in England is greater than this maximum. What if *average* traffic speed in a built-up area were greater than 30 mph?! OK, I know we’re dealing with different matters but you get the picture. There’s something not right – but, again, I’m not qualified to sort things out, but it would good if there were an answer. As a start I would like this page to show a recommended range (is it as simple as <5?) with a view as to how risks/concerns increase (and what they are) with increasing level.

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koebner said on 28 October 2010

to rodders995:
It's important to keep facts correct on this site since many people might be misguided by misguided and uninformed comments, for example your comments.
First, and perhaps least importantly for readers of this site, cholesterol is a sterol, hence the suffix 'sterol'. It is not an alcohol. Second, it is indeed a waxy substance on deposition. Third, triglycerides are indeed derived from our diet. They are converted to mono- or diglycerides by pancreatic lipase in the gut, absorbed in that form, then subsequently converted to triglycerides for distribution and storage in the body. Carbohydrates don't really come into the equation. Finally, and most importantly, you say we should not worry about cholesterol, implying that it plays no role in atherogenesis and cardiovascular disease. Your statement flies in the face of multiple large scale cross sectional surveys, case controlled trials, and randomised controlled trials. It is now clear that lowering cholesterol, for example by taking statins, significantly reduces mortality from cardiovascular disease and stroke. Interventional designs are the strongest support we have for a direct role of cholesterol in causing the pathology and disease. Sometimes drug companies do push drugs of questionable efficacy, but certainly not in this case. I only wish this site was moderated to remove reader's erroneous statements of fact potentially deleterious to the nation's health.

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Hepsi8 said on 22 October 2010

I agree entirely with the above comment.

Millions are now on statins. The public have been scared into taking them. GPs ar told it will keep their patients healthy and they go along with this. And the drug companies are laughing all the way to the bank.

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rodders995 said on 13 October 2010

I sincerely worry about the NHS when it can't get a basic fact correct.

Cholesterol is not a 'fatty substance' as the first line states. It is an alcohol, hence the 'ol' at the end.

The article then goes on to state, "Triglycerides are the fats you use for energy and come from the fatty foods you eat.". Again, this is wrong. Triglycerides come primarily from carbohydrate consumption.

And finally, there is very strong evidence that cholesterol is NOT something we should worry about. In older people, it appears to be protective.

I'm sorry, but 1/10 for this effort.

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