An Observational Cohort Study Evaluating Fatty Liver Disease and Liver Fibrosis in Moderate to Severe Psoriasis

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Recruitment status:
Recruiting
Primary Sponsor:
King's College London
Recruitment countries:
United Kingdom
Health condition studied:
Fatty Liver
URL:
Link to the clinical trial website

About the trial

Interventions:
Device: Transient elastography
Key inclusion and exclusion criteria:

  • Inclusion Criteria:

    - Patients who have given written informed consent

    - Psoriasis patients - chronic plaque-type psoriasis; PASI of 10 or above currently or
    in past.

    - 18 yrs. of age

    Exclusion Criteria:

    - Patients who have not given written informed consent

    - Patients under 18 yrs. of age

    - Patients with a PASI less than 10.

    - Pregnant women
  • Age minimum:  18 Years
  • Age maximum:  N/A
  • Gender:  Both
Primary outcomes:
Number of participants with liver fibrosis.
Secondary outcomes:
Number of participants with fatty liver disease diagnosed by ultrasound
Target sample size:
380
Study type:
Observational
Study design:
Observational Model: Cohort, Time Perspective: Prospective
Contacts:
  • Name:   Catherine H Smith, MD FRCP
  • Address: 
  • Phone: 
  • Email: 
  • Affiliation:  Guys and St Thomas' Hospitals Foundation Trust and King's College London
  • Name:   Catriona Maybury, MbChB
  • Address: 
  • Phone: 
  • Email:  catriona.maybury@kcl.ac.uk
  • Affiliation: 
  • Name:   Jonathan Barker
  • Address: 
  • Phone:  0207188 6412
  • Email: 
  • Affiliation: 
  • Name:   Jonathan N Barker, BSC MD FRCP
  • Address: 
  • Phone: 
  • Email: 
  • Affiliation:  King's College London

Technical details

Scientific title:
An Observational Cohort Study to Evaluate Factors Affecting Prevalence of Fatty Liver Disease and Fibrosis and Factors Affecting Response to Treatment in Patients With Psoriasis
Sources of monetary support:
Please refer to primary and secondary sponsors
Secondary sponsors:
Pfizer
Main ID:
NCT02174367
Secondary ID:
11/LO/1236
WS1851782
Register:
ClinicalTrials.gov
Date of registration:
22/05/2014
Date of first enrollment:
November 2012
Last refreshed:
19 February 2015

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