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Toxic shock syndrome

Introduction 

Toxic shock syndrome (TSS) is a rare, life-threatening bacterial infection. The bacteria responsible, staphylococcus aureus, invade the body's bloodstream and release poisonous toxins.

These toxins cause a massive drop in blood pressure resulting in symptoms of shock. They also begin to damage tissue, including skin and organs and can disturb many vital organ functions. Left untreated, the combination of shock and organ damage can result in death.

Around 20 people develop TSS in the UK every year, of which two or three will die because of the condition.

The condition is more common amongst young people, particularly in women under the age of 25. It is thought that this is because many older people have developed immunity to the toxins produced by the bacteria. However, cases have been recorded in people of all ages, including children.

For reasons that are still not understood, a significant proportion of cases occur in women who are menstruating and using a tampon. Particularly tampons designed to be "super absorbent".

TSS can also occur as a result of an injury, burn or as a complication of a localized infection such as a boil.

If detected early enough, treatment for TSS is normally successful. Treatment includes using antibiotics while providing support to the other functions of the body that have been affected by TSS.

  • show glossary terms
Shock
Shock is a short-term state of body weakness that usually happens after an accident of injury, caused when there is an insufficient supply of oxygen to the body.
Bacteria
Bacteria are tiny, single-celled organisms that live in the body. Some can cause illness and disease and some others are good for you
Blood
Blood supplies oxygen to the body and removes carbon dioxide. It is pumped around the body by the heart.
Tissue
Body tissue is made up of groups of cells that perform a specific job, such as protecting the body against infection, producing movement or storing fat
Antibiotics
Antibiotics are medicines that can be used to treat infections caused by micro-organisms, usually bacteria or fungi. For example amoxicillin, streptomycin and erythromycin

Last reviewed: 12/03/2008

Next review due: 12/03/2010

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