Thyroid, overactive

Introduction 

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An endocrinologist explains what causes an overactive thyroid gland, and the variety of treatment options.

Hyperthyroidism, also known as thyrotoxicosis or overactive thyroid, is a condition that occurs when there is too much thyroid hormone in the body. The condition is more common in women than men.

What is the role of the thyroid gland?

The thyroid gland is found in the neck. It produces hormones that are released into the bloodstream to control the body's growth and metabolism. These hormones are called thyroxine and triiodothyronine. They affect processes such as heart rate and body temperature, and help to turn food into energy to keep the body going.

Normally, the levels of thyroxine and triiodothyronine in the blood are carefully controlled so that these processes happen at a stable rate. However, in hyperthyroidism, the thyroid gland produces an excess amount of thyroxine, or triiodothyronine, which speeds up the body's energy consumption functions. As a result, the metabolism is accelerated. This causes symptoms such as:

  • hyperactivity,
  • an increased appetite, and
  • sudden weight loss or gain.

Overt and subclinical hyperthyroidism

There are several causes of hyperthyroidism, although the most common is Graves' disease, in which the body's immune system targets the thyroid gland and causes it to produce too much thyroid hormone.

Once diagnosed, hyperthyroidism can be classed as either:

  • overt, which means that it causes symptoms, or
  • subclinical, when the levels of thyroid hormone are still within normal limits.

If it isn't successfully controlled, hyperthyroidism can cause several other health problems, such as heart dysrhythmia (irregular heart rhythms) and osteoporosis (weak, brittle bones).

If left untreated hyperthyroidism can be fatal. However, the condition can be treated effectively using medicines to slow the production of hormones from the thyroid gland, as well as radiotherapy and, in some cases, surgery.

  • show glossary terms
Tissue
Body tissue is made up of groups of cells that perform a specific job, such as protecting the body against infection, producing movement or storing fat.  
Thyroid gland
The thyroid gland in the throat makes hormones to help control growth and metabolism (the process that turns the food we eat into energy).
Nodules
A nodule is a small growth or lump of tissue.
Blood
Blood supplies oxygen to the body and removes carbon dioxide. It is pumped around the body by the heart.

Last reviewed: 17/03/2008

Next review due: 17/03/2010

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