Stroke - Causes 

Causes of stroke 

Stroke

Someone has a stroke every five minutes in the UK, and strokes are the third most common cause of death. The cause varies from person to person but it's important to know what your personal risk factors are.

Media last reviewed: 14/11/2013

Next review due: 14/11/2015

Stroke is a largely preventable condition. Many risks can be reduced by making lifestyle changes.

However, some things that increase the risk of stroke cannot be changed, including:

  • age – you are more likely to have a stroke if you are over 65 years old, although about a quarter of strokes happen in younger people
  • family history – if a close relative (parent, grandparent, brother or sister) has had a stroke, your risk is likely to be higher
  • ethnicity – if you are south Asian, African or Caribbean, your risk of stroke is higher, partly because rates of diabetes and high blood pressure are higher in these groups
  • your medical history – if you have previously had a stroke, TIA or heart attack, your risk of stroke is higher

Ischaemic strokes

Ischaemic strokes, the most common type of stroke, occur when blood clots block the flow of blood to the brain. Blood clots typically form in areas where the arteries have been narrowed or blocked by fatty cholesterol-containing deposits known as plaques. This narrowing of the arteries is caused by atherosclerosis.

As we get older our arteries become narrower, but certain things can dangerously accelerate the process. These risks include:

Diabetes is also a risk factor, particularly if poorly controlled, as the excess glucose in the blood can damage the arteries.

Another possible cause of ischaemic stroke is an irregular heartbeat (atrial fibrillation), which can cause blood clots that become lodged in the brain. Atrial fibrillation can be caused by:

  • high blood pressure 
  • coronary artery disease 
  • mitral valve disease (disease of the heart valve) 
  • cardiomyopathy (wasting of the heart muscle) 
  • pericarditis (inflammation of the bag surrounding the heart) 
  • hyperthyroidism (overactive thyroid gland)
  • excessive alcohol intake 
  • drinking lots of caffeine; for example, tea, coffee and energy drinks

Haemorrhagic strokes

Haemorrhagic strokes (also known as cerebral haemorrhages or intracranial haemorrhages) usually occur when a blood vessel in the brain bursts and bleeds into the brain (intracerebral haemorrhage). In about 5% of cases, the bleeding occurs on the surface of the brain (subarachnoid haemorrhage).

The main cause of haemorrhagic stroke is high blood pressure (hypertension), which can weaken the arteries in the brain and make them prone to split or rupture.

Things that increase the risk of high blood pressure include:

  • being overweight or obese
  • drinking excessive amounts of alcohol 
  • smoking
  • a lack of exercise 
  • stress, which may cause a temporary rise in blood pressure

Another important risk of haemorrhagic stroke is treatment with medicines given to prevent blood clots, such as warfarin.

Haemorrhagic stroke can also occur from the rupture of a balloon-like expansion of a blood vessel (aneurysm) and badly-formed blood vessels in the brain.

A traumatic head injury can also cause bleeding into the brain. In most cases, the cause is obvious, but bleeding into the lining of the brain (subdural haematoma) can occur without any obvious signs of trauma, especially in the elderly. The symptoms and signs can then mimic a stroke.

 

Page last reviewed: 29/08/2012

Next review due: 29/08/2014

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The 2 comments posted are personal views. Any information they give has not been checked and may not be accurate.

Monkfish said on 17 April 2011

An observation, Could allergen be a contributing if not actual cause of stroke? the most sticky ones e.g. Cat Fel D 1 amongst others. Also isn't curvature of spine in old age causing pressure on vertebral arteries more certainly a cause?

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Sherlin said on 05 August 2010

Almost 90 percent of strokes are ischemic strokes. They occur when the arteries to your brain are narrowed or blocked, causing severely reduced blood flow (ischemia). Lack of blood flow deprives your brain cells of oxygen and nutrients, and cells may begin to die within minutes. The most common ischemic strokes are: Thrombotic stroke and embolic stroke. In Thrombotic stroke a blood clot is formed in one of the arteries that supply blood to your brain. Whereas in Embolic stroke, an embolic stroke occurs when a blood clot or other debris forms in a blood vessel away from your brain — commonly in your heart.

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