Restless legs syndrome - Treatment 

Treating restless legs syndrome 

Cardiovascular disease

Research has found that people with RLS are twice as likely to develop cardiovascular disease (CVD) than the population at large. It is not known exactly why.

The more severe the symptoms, the greater the increase in risk.

You can take steps to reduce your risk of CVD, such as regularly exercising, maintaining a healthy weight, quitting smoking if you smoke and eating a healthy diet.

Read more about preventing cardiovascular disease.

If your restless leg syndrome (RLS) is known to be linked to an underlying cause, then treating that cause can often lead to a complete cure.

For example, iron deficiency can be treated by taking iron supplements, and RLS associated with pregnancy usually goes away on its own within four weeks of the birth.

If RLS has no obvious cause, then treatment falls into one of two categories:

  • lifestyle changes
  • medication

Lifestyle changes

A number of lifestyle changes may be enough to ease the symptoms of RLS. These include:

  • avoiding stimulants, such as caffeine, tobacco and alcohol
  • not smoking
  • taking regular, daily exercise – but avoid exercising near bedtime
  • establishing a regular sleeping pattern – for example, going to bed and getting up at the same time every day; not napping during the day; taking time to relax before going to bed; avoiding caffeine close to bedtime
  • avoiding medicines that trigger the symptoms of RLS or make them worse – if you think your medication is causing your symptoms, continue taking it and make an appointment to see your GP.

During an attack of RLS, you may find the following measures helpful in relieving symptoms:

  • massaging your legs
  • taking a hot bath in the evening
  • applying a hot or cold compress to your leg muscles
  • doing activities that distract your mind, such as reading or watching television
  • relaxation exercises such as yoga or tai chi
  • walking and stretching

On this last point a small medical trial carried out in 2011 found that a type of osteopathic exercise technique called positional release manipulation (PRM) could be of benefit to people with RLS.

PRM involves holding different parts of the body in position that has been found to reduce feelings of discomfort and pain.

Though larger studies will be required before it is clear that PRM is an effective treatment for most cases of RLS.

(Osteopathy is a complementary or alternative medicine that claims to be a way of detecting, treating and preventing health problems by moving, stretching and massaging a person’s muscles and joints.) 

Medication

Levodopa

Levodopa may be recommended if you only have symptoms now and again. This is because if you took levodopa every day, there is a high risk that it would actually make your symptoms worse.

Levodopa is available in tablet or liquid form and you should take it once you feel the symptoms of RLS coming on.

The medication will make you feel very sleepy, often very suddenly, so you should never drive or use tools or machinery after taking levodopa.

Levodopa can cause nausea, so it is usually combined other medications to reduce the nausea.

Dopamine agonists

Dopamine agonists are usually recommended if you are having more frequent symptoms. They include:

These medications can make you feel very sleepy so you should never drive or use tools after taking them.

Other side effects of these medications include:

  • nausea
  • dizziness
  • headache

Another dopamine agonist called cabergoline has proved to be effective in the treatment of RLS but tends only to be used if the medications mentioned above prove ineffective. This is because it can cause a range of serious side effects, which your GP will discuss with you.

Painkillers

You may need to be prescribed a mild opiate-based painkiller such as codeine or tramadol to relieve any pain associated with RLS.

Side effects of these types of painkillers include:

Another medication that can be used to both relieve pain and relieve symptoms of RLS is gabapentin. Side effects of gabapentin include dizziness and feeling tired and sleepy.

Aiding sleep

If you are having a particularly severe flare-up of symptoms that is disrupting your sleep, it may be recommended that you take a short-term course of medication to help you sleep.

These types of medications are known as hypnotics and include temazepam and loprazolam.

Hypnotics are usually only recommended to be used on short-term basis (typically no longer than week).

You may find you still feel sleepy or 'hungover' the next morning after taking your medication. 


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Last reviewed: 31/10/2011

Next review due: 31/10/2013

Comments are personal views. Any information they give has not been checked and may not be accurate.

kaoskatt said on 20 April 2012

I have suffered from this for years, especially since I also succumbed to rheumatoid arthristis in 2000. A couple of years ago, a friend who also has issues with RLS suggested I try a glass of tonic water when afflicted - but it had to be Schweppes or similar genuine tonic containing quinine [not ones with just the flavouring]. I now keep diet tonic by my bedside and can report that drinking a small glass of it [under half a pint] subdues my symptoms within 15 minutes. I have no idea why, but it works for me every time.

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greystone said on 16 April 2012

I have suffered with this complaint for the past 30 yrs my father also had it we both used the same system as prevously described by RLSsufferer and Soowhizz and that is the tiptoe stretch but for me after all these years I have to get up to about 100 before the calf muscle tighten's up and the relief comes, I sometimes follow that with some stretching by touching my toes either reaching down to the floor or by siting on the floor and reaching forwards. It only works for me after the symptom's have come on, so at 2am in the morning it's not great but effective ! Over the years I have tried all the pills and potions and this is the only thing that is effective for most of the time , but some nights it's just grit yur teeth and bear it . Hope this helps someone.

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belinda666 said on 05 November 2011

omg i never heard off rls.ive had it getting on for 2yrs and no sleep,it makes you deppresive to,i feel like ime addicted to painkillers,but reading this its time i went to the docs,its an absolute ngtmare,i feel like its taken over my lifeive got it bad i fidget all ngt,i feel exhausted to be honest.i never dreamed other people suffer to,i cant bare the thought off having this the rest off my life,love and best wishes to you all xxxxxxxxxxxx

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tpws said on 19 October 2011

I have had RLS for about 6 years now and it is getting worse I am now taking ropinirole 3 mg just to get through the night.
I take Citalopram for stress which I'm told makes the RLS worse, but as yet no one has come up with an alternative.
If anyone can help out there that would be great.

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Soowhizz said on 11 March 2011

I have suffered with RLS for a number of years now and I do exactly the same as you do to relieve it. I can then get back in to bed and go to sleep!

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RLSsufferer said on 30 June 2010

I have suffered with RLS for nearly 2 years, since I was pregnant. It advises not to exercise just before bed. I have found that my calf muscles feel too active at night and need wearing out. So either just before bed, or after the RL symptoms have started, I stand up on my tiptoes and slowly lower my heels to the floor (like calf raising exercises) 15-20 times. This seems to wear my legs out sufficiently to relieve the symptoms and allow me to sleep. I didnt think anything of what I was doing, until I overheard a pregnant lady complaining of her restless legs. Like me she had tried stretching and it didnt work. I demonstrated the exercises I do to her. She came back to mea week later and told me they work a treat and I should share the advice. So I hope this helps people. I would love to know if they work for anyone else?

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Unlicensed medication

Not all medicines used to treat RLS are licensed in the UK.

If a medicine is licensed, it means it has been approved by the Medicines and Healthcare Regulatory Agency (MHRA) as a safe and effective form of treatment.

Unlicensed medicines are not necessarily unsafe. They can be prescribed if a health professional feels that the potential benefit of the medication outweighs any possible risk.

The medicine may be unlicensed because there is not enough commercial interest in marketing it, or because it is awaiting approval for a license. If a medicine is unlicensed, it is up to your GP to decide whether they prescribe it to you.

Getting ready for bed

If you have difficulty nodding off, a regular bedtime ritual will help you wind down and prepare for sleep