Rabies - Causes 

Causes of rabies 

The rabies virus belongs to a group of viruses called lyssaviruses, which exist in warm blooded animals. The disease is transmitted through infected saliva.

Rabies can spread to humans from infected animals, usually dogs, through a bite or a lick to broken skin or the eye. Domestic dogs and cats can become infected with rabies if they come into contact with wild animals that have the disease, such as foxes, wolves, jackals, skunks, mongooses, raccoons and bats.

The rabies virus remains at the site of the bite and multiplies in the muscle cells near to the bite wound, before entering the body. The virus enters the nerve endings and travels to the spinal cord and brain (the central nervous system). Once the virus is in the central nervous system, it will spread to the salivary glands, lungs, kidneys and other organs.

Incubation period

The incubation period (the time between the bite and the onset of symptoms) will vary depending on the distance of the bite from the head.

If a bite occurs near the head, such as the neck or face, then the rabies virus has a shorter journey to travel to the brain. So the incubation period is shorter than in bites to the legs and feet.

Children, particularly young children, tend to have relatively a short incubation period than adults. This is because children are shorter, so their upper body is closer to the ground, making them more vulnerable to bites higher up the body.

  • show glossary terms
Brain
The brain controls thought, memory and emotion. It sends messages to the body controlling movement, speech and senses.
Disease
A disease is an illness or condition that interferes with normal body functions.
Kidneys
Kidneys are a pair of bean-shaped organs located at the back of the abdomen, which remove waste and extra fluid from the blood and pass them out of the body as urine.
Lungs
Lungs are a pair of organs in the chest that control breathing. They remove carbon dioxide from the blood and replace it with oxygen.
Onset
The onset is the beginning or early stages of a condition or disease.
Spinal cord
The spinal cord is a column of nervous tissue located in the spinal column. It sends messages between the brain and the rest of the body.

Last reviewed: 30/03/2011

Next review due: 30/03/2013

Animals that carry rabies

In developing countries, particularly those in Africa and Asia, the majority of rabies in humans happen when people are bitten by dogs. In South America, bats are another significant cause.

In developed countries, all warm blooded animals can carry rabies. However, some species are more commonly infected than others. For example:

  • bats
  • raccoons
  • foxes
  • jackals
  • wolves
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