Stomach ulcer - Causes 

Causes of stomach ulcers 

Lifestyle factors

In the past it was thought that stomach ulcers were caused by certain lifestyle factors, such as spicy foods, stress, smoking and alcohol. However, there is little hard evidence to confirm that this is the case.

It may be that although these types of lifestyle factors do not cause ulcers, they may make the symptoms of ulcers worse.

Does H pylori cause cancer?

H pylori is associated with a very slightly increased risk of stomach cancer. However, treating H pylori for this reason alone is not recommended. The risk of anyone getting stomach cancer is small and no one knows whether treating H pylori will actually reduce your risk of developing stomach cancer.

Stomach ulcers are usually caused by one of the following things:

  • H. pylori bacteria
  • non-steroidal anti-inflammatory drugs (NSAIDs)

Acid and mucus

The stomach produces acid to digest food.

The lining of the stomach is coated with mucus, which protects the lining from the harmful effects of the acid.

H. pylori and NSAIDs can break down the stomach's defence against acid, allowing the acid to cause an ulcer. Even though most people with ulcers are not producing too much acid, blocking the acid will allow the ulcer to heal and then the cause of the ulcer can be removed to prevent it coming back.

H. pylori

Helicobacter pylori (H. pylori) infections are very common, and it's possible to be infected without realising it because the infection doesn't usually cause symptoms.

It is not known why some people are vulnerable to the effects of H. pylori when the majority of people are not. However, smoking is a major risk factor that people can do something about.

Also, stomach ulcers are known to run in families, so there may be genetic factors that make certain people more sensitive to H. pylori. Some strains of H.pylori are more damaging than others.

NSAIDs

Non-steroidal anti-inflammatory drugs (NSAIDs) are medicines commonly used to treat:

Some people with cardiovascular disease (conditions that affect the heart and the blood) also take aspirin on a regular basis because it can reduce the risk of blood clots which can cause heart attacks and strokes.

NSAIDs that are available over the counter include:

  • ibuprofen
  • aspirin
  • naproxen

NSAIDs that are only available on prescription include:

  • diclofenac
  • etodolac
  • fenoprofen

Read more about non-steroidal anti-inflammatory drugs.

Because of the risk of getting stomach ulcers, you may be advised not to use NSAIDs if you currently have a stomach ulcer or if you have had one in the past. 

Paracetamol can often be used as an alternative painkiller as it is safer.

However, there may be cases where the benefits of taking NSAIDs is thought to outweigh the risk of developing stomach ulcers. For example, if you have recently had a heart attack, low-dose aspirin may be required to prevent you having another one.

In such circumstances, a medication called a proton pump inhibitor (PPI) can be used to reduce the amount of acid in your digestive system, which should help prevent ulcers from forming and reduce the risk of complications.

Read more about treating stomach ulcers with PPIs.

 



  • show glossary terms
Aches
An ache is a constant dull pain in a part of the body.
Anti-inflammatory
Anti-inflammatory medicines reduce swelling and inflammation.
Bacteria
Bacteria are tiny, single-celled organisms that live in the body. Some can cause illness and disease and some others are good for you.
Blood
Blood supplies oxygen to the body and removes carbon dioxide. It is pumped around the body by the heart.
Enzyme
Enzymes are proteins that speed-up and control chemical reactions, such as digestion, in the body.
Genetic
Genetic is a term that refers to genes- the characteristics inherited from a family member.
Inflammation
Inflammation is the body's response to infection, irritation or injury, which causes redness, swelling, pain and sometimes a feeling of heat in the affected area.
Pain
Pain is an unpleasant physical or emotional feeling that your body produces as a warning sign that it has been damaged.
Stomach
The sac-like organ of the digestive system. It helps digest food by churning it and mixing it with acids to break it down into smaller pieces.
Ulcer
An ulcer is a sore break in the skin, or on the inside lining of the body.

Last reviewed: 31/10/2011

Next review due: 31/10/2013

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NSAIDs

Non-steroidal, anti-inflammatory drugs (NSAIDs) can treat a wide range of symptoms such as headaches, toothache, muscle and joint pain, fever and inflammation

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