Oral thrush - adults - Treatment 

Treating oral thrush 

Oral thrush can be successfully treated using antifungal medicines.

Antifungal treatments are available in the following forms:

  • tablets
  • lozenges
  • powders
  • creams
  • rinses

Rinses are useful for people with a dry mouth who are unable to swallow antifungal tablets.

Antifungal medicines that can be used to treat oral thrush include:

  • fluconazole
  • itraconazole
  • nystatin
  • clotrimazole
  • miconazole
  • econazole
  • ketoconazole

If you are taking certain antibiotics or corticosteroids that are thought to be causing your oral thrush, the medicine may need to be changed or the dosage reduced.

Some antifungal medications should not be used if you are pregnant, breastfeeding or taking other medications. Always seek advice from your GP or pharmacist before taking antifungal medicines.

Side effects

Possible side effects of antifungal medicines include:

  • nausea (feeling sick)
  • tummy pain
  • diarrhoea 
  • headache
  • indigestion

If you wear dentures, an antifungal cream can be applied to the affected area of the roof of the mouth and to the bottom of the dentures. Antifungal lozenges are also effective. 

If the underlying cause of your oral thrush cannot be cured, you may need to continue taking antifungal treatment for a longer period of time.

See the Health A-Z topic about Antifungal medicines for more information about this type of treatment.

Last reviewed: 13/09/2010

Next review due: 13/09/2012

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Comments are personal views. Any information they give has not been checked and may not be accurate.

Ytterbia said on 05 July 2011

My attack of thrush was caused by taking a new antibiotic. I needed some help to decide whether to treat it or just suffer it till the antibiotics are finished. So, since you have advised seeking medical advice before taking anti-fungal medicines, I have decided to wait a few days then see my GP if it doesn't clear up. Thank you.

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Jenny Dobson said on 27 September 2010

This page has recently been reviewed and updated following user feedback and now includes information for non-denture wearers.

NHS Choices content team

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donrem49 said on 16 August 2010

What about people who do not have dentures! What treatment are they supposed to have?

The advice here is useless. I don't wear dentures yet have my first and a bad attck of oral thrush. I came here looking for some information and got advice on how to keep my dentures clean - rubbish.

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Oral thrush and HIV or AIDS

If you have HIV or AIDS and you develop oral thrush, this may be treated slightly differently. See the links below for more information.