HPV vaccination

Side effects of HPV vaccination  

The Yellow Card Scheme allows you to report suspected side effects from any type of medicine that you are taking. It is run by a medicines safety watchdog called the Medicines and Healthcare Products Regulatory Agency (MHRA). See the Yellow Card Scheme website for more information.

Following clinical trials, the vaccine used in the UK HPV vaccination programme (Cervarix) was shown to cause side effects in some people.

Very common side effects

Very common side effects are:

  • pain or discomfort at the injection site,
  • redness or swelling at the injection site,
  • headaches,
  • aching muscles, muscle tenderness or weakness (not caused by exercise), and
  • tiredness.

These may occur in more than one per 10 doses of vaccine.

Common side effects

Common side effects are:

  • gastrointestinal symptoms including nausea, vomiting, diarrhoea and abdominal pain,
  • itching, red skin rash or hives (urticaria),
  • joint pain, and
  • fever (a body temperature of 38°C or over).

These may occur in less than one per 10 doses of the vaccine but more than one per 100 doses.

Uncommon side effects

Uncommon side effects are:

  • upper respiratory tract infection (infection of the nose, throat or windpipe),
  • dizziness, and
  • other injection site reactions such as a hard lump, tingling or numbness.

These may occur in less than one per 100 doses of the vaccine but more than one per 1,000 doses.

Very rare side effects

In very rare cases, it is possible for someone who has the vaccine to experience a more severe allergic reaction, known as an anaphylactic reaction. Signs of an anaphylactic reaction include difficulty breathing and collapse.

However, it should be stressed that severe reactions of this nature are very rare and, when they do occur, the health professional who is giving the vaccine will have been fully trained in how to effectively deal with it. If your child has an anaphylactic reaction following treatment, they will usually fully recover within a few hours.

Last reviewed: 17/09/2008

Next review due: 17/09/2010

What are these?

crg101 said on 26 January 2010

I am 19yrs old and had the HPV jabs in Dec 08, Jan 09 and June 09. I have experienced nausea, diarrhoea and an upset stomach/ digestive problems ever since (about 6 or 7 months now).
It's really frustrating because I thought it was a really good idea to protect myself against cervical cancer but I have had health problems ever since so seriously wish I hadn't had these jabs.
I think it's too early to say that these vaccines are "safe" because it is relatively new and there are at least 1300 people suffering from adverse effects, including myself.
I read an article which said that the jabs have a salmonella bacterium in them which stimulates the immune system and think this is probably why I am ill.
I have had 3 blood tests, a breath test and an ultrasound scan and have still not got to the bottom of my illness.

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Flo91 said on 26 January 2010

I am 18 and recieved my second HPV vaccine last week, which was late as I was not permitted to reciece my first one as I had a temperature and was on Antibiotics at the time.

Admittedly, both times I have recieved the vaccine I have had horrible side effects, including blinding migranes, nausea, fainting spells, vomiting, dizziness, a high temperature, aching muscles and severe pain in the arm. However, these only lasted two days, and I would much rather experience these knowing that I am a lot safer from cervical cancer than missing this oppurtunity to skip these symptoms.

It is ridiculous to pass this chance up because of being frightened of a couple of days of side effects, and even more ridiculous to forbid your daughter to on her behalf, as it is her own body who would be missing out on the innoculation.

I can confirm, the only side effects I was warned about was the possibility of a headache, faintness, and a sore arm, but if anyone uses their common sense then they could realise that they are bound to feel rather poorly after any vaccine, considering the nature of the action.

I do not regret agreeing to these vaccines, I would so much rather put up with a couple of days of feeling poorly than the possibility of getting cervical cancer in the future. I strongly advise anyone who is offered the chance to get the vaccine to recieve it rather than take the risk with cervial cancer.

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School girl said on 21 January 2010

I'm a fifteen year old girl and today i had my second HPV injection. To all those that are passing this up is rediculous. The bad side affects are really rare. All i get is a slight headache and soreness around the injected area fo 24 hours. I would much rather deal with that then actually get cervical cancer. Your daughters are at the age where they can make up their own mind about things and this is definately one of them! I highly recommend! The injection doesn't even hurt. So i think your putting your daughter more at risk from it by not letting her have it because she may not be old enough for screening but doesn't mean she won't get it at her age.

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AuntyEm14 said on 12 December 2009

I had my first vaccination yesterday and I have so many side effects. Aching muscles, tiredness and headaches. Then in the next section nausea, diarrhoea, abdominal pain and a fever. I have even add dizziness in the next section. I realise I will probably get these each time but because of what it does I guess I will have to let it slide.

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lidia95 said on 23 November 2009

im 14 and ha jab today i have go a very swollen arm around where the jab is . is this normal. and i felt very faint but school wouldnt send me home. :@

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itshayleyx said on 17 November 2009

I Am 14 years old I Got my HPV vaccination on the 16th November and i only got some of the common side effects like tiredness, sore head and it is sore around the area i got injected. i still have a pain in my arm the day after but it isint as bad. i think if you have the chance to get it, get it.

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Luthey said on 23 October 2009

I am 19 and earlier this year was offered the HPV vaccine as part of the catch up scheme which is currently taking place.

As I am a student nurse I looked into the theoretical research regarding, as well as the clinical trials, which have taken place for this vaccine.

Considering all the information given to me, combined with my reading, I decided to have the Cervarix Vaccine. I suffered no side effects except for a slight aching in my arm after each injection was given.

I am very grateful that I was offered the vaccine and feel that although, because I am older, there is a chance it will not give me maximum protection, I am still up to 70% less likely to suffer from this cancer.

Personally, when I weighed the risk of cervical cancer against the risk of side effects, the latter seemed incomparable. I respect and understand that it is easier for me to make this decision for myself; I cannot expect to understand how it feels to make it for your children. However, the research and the information is out there.

I made the educated decision to have the vaccine and hope that this along with regular screening when the time comes will help protect me from cervical cancer.

Lucy

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Caspar said on 02 October 2009

Dear JAMSRM,

Please have a look at our HPV vaccine Q&A page which may help put your fears to rest.

http://www.nhs.uk/news/2009/09September/Pages/Cervical-cancer-vaccine-QA.aspx

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JAMSRM said on 01 October 2009

My daughter is due her first dose of HPV next week and I'm seriously considering withdrawing her from the programme. In fact, after reading these pages and the various comments I agree whole heartedly with Mr and Mrs G Martin that the full facts should be made transparent to parents and because they are not I will be cancelling my daughter's participation first thing tomorrow morning. I know that cervical cancer is a terrible disease but if you're screened regularly enough it can be caught at the very early stages and it is treatable. I am screened regularly and I'll make sure that my daughter is when she is old enough.

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Linda 1963 said on 29 September 2009

How long would it take for the side affects to start after the injection is given ??

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Laura1108 said on 25 August 2009

I have recently finished my course of the HPV vaccination. I was shocked to read the above side effects of which i was not advised of at the time.

However i was absoluteley fine, apart from sensitive soreness and mild swelling.

It is definatley worth putting up with a sore arm for the following 24 hours than being at risk and suffering the catastrophic effects of cervical cancer in the future

Laura, 18

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jackieh said on 28 June 2009

I agree with garethm. I read a lot about reported side effects and expected to find some balanced information on which to make a judgement. However in the absence of any of these reportsbeing mentioned at all together with the fact s that my daughter has been generally unwell for some months and had a bad reaction to MMR when she was younger I have also declined the vaccine for my daughter.
Mrs J Hilton

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Caspar said on 09 June 2009

The Department takes the safety of vaccines very seriously. As with any vaccine or medicine, the HPV vaccine Cervarix can cause side effects in some individuals and the Medicines and Healthcare products Regulatory Agency (MHRA) is closely monitoring the safety of the vaccine. Such potential risks must be balanced against the benefits of Cervarix in protecting against cervical cancer.

Suspected side effects to vaccines are reported to the MHRA through the Yellow Card Scheme - http://yellowcard.mhra.gov.uk/ . It is essential to bear in mind a report received through the MHRA Yellow Card Scheme relates only to a suspicion, by the reporter, that a vaccine or drug may have caused the medical condition. These reports cannot be considered proof of a side effect. Therefore, reports may be true side-effects or they may have been caused by coincidental medical conditions resulting from underlying or undiagnosed illness and, as such, would have occurred even in the absence of vaccination.

In the case of Cervarix, the MHRA has proactively encouraged reporting of Yellow Cards by writing to all health professionals involved in the vaccine programme and via its website and Drug Safety Update bulletin. Because of this, and based on past experience with other major new immunisation programmes, the number of Yellow Card reports received to date is fully in line with what was expected at this stage in the programme and no serious new risks have been identified. The Commission on Human Medicines recently reviewed the adverse reactions reported in association with Cervarix and advised that the balance of risks and benefits remains positive.

Further information can be found on the MHRA website - http://www.mhra.gov.uk/HPVvaccine . The safety of Cervarix continues to remain under close and continual review by the MHRA.

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garethm1962 said on 04 June 2009

RE: lack of warning over side effects following HPV Vaccinations

We are surprised that following recent horror stories on side effects on the 'new' HPV vaccine, there is still little warning of such possible side effects in the leaflets or website. Some 1,300 children have sufferered adverse reactions.

As you should be aware vaccines do not also distribute evenly throughout the body, and can cause severe reaction for a considerable time.

In order for parents to make an informed decision, all available un-biased information must be provided.

It is a concern that parents are NOT being given the full balanced facts.

Despite a certain amount of pressure we ourselves declined that our daughter have the series of inoculations.

We are surprised that local schools are continuing with this treatment until the drug is properly tested, and have written (and will continue to write) to our MP and local paper about this matter

We will be monitoring your website for additional information in order for parents to make their own judgement whether the risk to health is acceptable

yours faithfully

Mr & Mrs G. Martin

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