Uncomplicated gallstone disease
The most common symptom of uncomplicated gallstone disease is a type of abdominal pain known as biliary colic.
Biliary colic
Biliary colic is a sudden, intense pain that usually lasts between one and five hours (although sometimes it can last up to eight hours). The pain can be located in:
- the centre of your abdomen, below your breastbone and above your umbilicus (bellybutton)
- the upper right of your abdomen, with the pain radiating towards your shoulder blade
You will usually find that the pain of biliary colic is brought on by eating fatty foods. The pain may also wake you up during the night.
Biliary colic is usually an infrequent symptom of gallstone disease. After an episode of pain, it may be several weeks or months before you experience another episode.
In addition to the pain associated with biliary colic, a number of people also experience:
- nausea
- vomiting
- excessive sweating
Complicated gallstone disease
The three most common complications that can arise from complicated gallstone disease are:
- inflammation of the gall bladder (acute cholecystitis)
- inflammation of the bile ducts (acute cholangitis)
- inflammation of the pancreas (acute pancreatitis)
Acute cholecystitis
Acute cholecystitis can develop when one of your bile ducts becomes blocked by gallstones. The blockage causes the gallbladder to become swollen, irritated and inflamed.
Symptoms of acute cholecystitis include:
- pain in your upper abdomen that radiates towards your shoulder blade (unlike biliary colic, the pain usually lasts longer than five hours)
- a high temperature (fever) of 38C (100.4F) or above
- a rapid heartbeat
An estimated 15% of people with acute cholecystitis will also have symptoms of jaundice.
Acute cholangitis
If the bile ducts become blocked, they are vulnerable to infection by bacteria. Infected bile ducts may become inflamed.
Symptoms of acute cholangitis include:
- pain in your upper abdomen that radiates towards your shoulder blade
- a high temperature
- jaundice (yellowing of the skin and whites of the eyes)
- chills
- mental confusion
- itchy skin
- a general sense of feeling unwell
Acute pancreatitis
Acute pancreatitis may develop when a gallstone moves out of the gallbladder and blocks the opening (duct) of the pancreas, causing it to become inflamed.
The main symptom of acute pancreatitis is the sudden onset of pain in the centre of your upper abdomen.
The pain of acute pancreatitis often gets steadily worse until it reaches a constant ache. The ache can be severe and may travel from your abdomen and along your back. The pain may feel worse after you have eaten.
Leaning forward or curling up into a ball may help relieve the pain to some extent.
Other symptoms of acute pancreatitis can include:
- nausea
- vomiting
- diarrhoea
- loss of appetite
- a high temperature (fever) of 38C (100.4F) or above
- tenderness of the abdomen
- less commonly, jaundice (yellowing of the skin and whites of the eyes)
When to seek medical advice
The best way to determine whether your symptoms are due to uncomplicated gallstone disease or complicated gallstone disease is to determine whether:
- you have a high temperature
- your symptoms of pain last longer than eight hours
If you do not have either of these two symptoms, it is likely that you have uncomplicated gallstone disease and you should make an appointment to visit your GP.
If you have either of the above two symptoms, contact your GP immediately for advice. If this is not possible, phone your local out-of-hours service or call NHS Direct on 0845 46 47.
In some cases, complicated gallstone disease may be an emergency as it can lead to serious complications if it is left untreated. Therefore, it is advisable to get an expert opinion on your symptoms as soon as possible.