Endocarditis 

Introduction 

Endocarditis is a rare and potentially fatal type of heart infection.

It's specifically an infection of the inner lining of the heart (the endocardium), most commonly caused by bacteria entering the blood and travelling to the heart.

The heart is well protected against infection and bacteria usually pass by without causing any harm. However, if the heart valves are damaged, or if a person has an artificial valve (see below), it's easier for bacteria to take root and bypass your normal immune response to infection.

Read more about the causes of endocarditis.

The initial symptoms of endocarditis are similar to the flu and include:

  • a high temperature (fever) of or above 38C (101.4F)
  • chills
  • loss of appetite
  • headache
  • joint pain

Left untreated the infection will damage the valves of the heart, disrupting the normal flow of blood through the heart.

This triggers a range of life-threatening complications, such as:

  • heart failure – where the heart is unable to pump enough blood around the body to properly meet the body’s demands
  • stroke – where the supply of blood to the brain becomes disrupted

Read more about the symptoms of endocarditis.

Treating edndocarditis

Endocarditis is treated with a course of antibiotics given via a drip, you will need to be admitted to hospital for this.

Around 1 in 5 people will also need surgery to repair or replace a damaged heart valve or drain away any abscesses that develop (an abscess is a large collection of pus).

Read more about the treatment of endocarditis.

Who is affected

You are more at risk of developing endocarditis if you:

  • have a prosthetic (artificial) heart valve – valve replacement surgery is increasingly being used when people experience narrowing of one their heart valves
  • have congenital heart disease – congenital heart disease means a person is born with heart defects
  • have damaged heart valves – due to infection or heart disease
  • inject drugs such as heroin – heroin users are three times more likely to develop endocarditis than the population at large

Even in these higher-risk groups endocarditis remains a rare condition.  In England, for example, endocarditis is estimated to affect around 1 in every 3,000 people in any given year.

Endocarditis is more common in older people, with half of all cases developing in people over 50. However, cases of endocarditis have been recorded in children, particularly those who are born with congenital heart disease. Twice as many men are affected as women.

Although it may sound strange, rates of endocarditis are increasing due to advancements in medical care. This is because an increasing number of people are now being treated with valve replacement surgery or surgery to repair congenital heart disease.

Outlook

Endocarditis is a serious illness and even with the highest standard of medical care the risk of dying is high – at around 1 in 5.




  • show glossary terms
Bacteria
Bacteria are tiny, single-celled organisms that live in the body. Some can cause illness and disease and others are good for you.
Brain
The brain controls thought, memory and emotion. It sends messages to the body controlling movement, speech and senses.
Heart valves
Heart valves are four sets of flaps that control the direction that blood pumps around the heart.
Inflammation
Inflammation is the body's response to infection, irritation or injury. It causes redness, swelling, pain and sometimes a feeling of heat in the affected area.
Kidneys
Kidneys are a pair of bean-shaped organs located at the back of the abdomen. They remove waste and extra fluid from the blood and pass them out of the body as urine.
Lungs
Lungs are a pair of organs in the chest that control breathing. They remove carbon dioxide from the blood and replace it with oxygen.
Tissue
Body tissue is made up of groups of cells that perform a specific job, such as protecting the body against infection, producing movement or storing fat.

Last reviewed: 23/02/2012

Next review due: 23/02/2014

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Comments are personal views. Any information they give has not been checked and may not be accurate.

Bride2 said on 18 June 2012

I had endocarditis op in 2001 following a problem with hickman line[which I had in for regular blood transfusions for mylodysplasia] & a vegetative mass on the end of it.
My husband was warned I would either be dead or brain damaged. Then not a lot was known about this disease.
11 years on I get tired easily and need anti biotics when I go for dental treatment, but I take each day with a flourish.
Since the op I have been widowed and re married

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staceyfr88 said on 08 May 2012

I found this very interesting as I was diagnosed with endocarditis at the age of 7. I t was also at this age that doctors discovered I had congenital valvular stenosis, which caused the infection. In the beginning I went through weeks and weeks of painful headaches and swollen joints. GPs were teeling my mum it was just anemia and for a while I was on iron tablets which did nothing. My mum persisted on further tests and I remember an ambulance arriving at th GPs and I was taken to John Radcliffe hospital in Oxford. I had 2 major procedures in 1 op. My aorta was replaced and my spleen was removed as it was so infected (my other organs had a very lucky escape) I then had 4 blood transfusions following my op and was in intensive care for 2 weeks. I am 24 now and pregnant with my first baby. He has had a heart scan done already and will have one again when he is born and when he reaches his teens. I really do hope he doesn't inherit the condition but know that this time it will be caught early and dealt with alot faster. If it had not been for my mums persistance, the organ donor and blood donors I would not be here today. Im very lucky to be alive! Its good to now know what my condition was and what caused it because until reading this decription I didnt have a clue.

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