Cystitis - Causes 

Causes of cystitis 

What do our kidneys do?

The kidneys filter waste products from the blood before turning it to urine. This video explains in detail how the kidneys function.

Cystitis and menopause

In women who have had, or are going through, the menopause, the lining of the urethra and the bladder become thinner. This is due to a lack of the hormone oestrogen. The thin lining is more likely to become infected or damaged. Women also produce fewer vaginal secretions after the menopause, and this means bacteria are more likely to multiply.

Find out more about the menopause.

Ketamine link

People who have been prescribed ketamine for pain relief, or recreational drug users who use it as a "dance drug" in clubs, have suffered severe cystitis as a result. Long-term ketamine users risk developing kidney failure and permanent damage to the urinary tract.

The most common cause of cystitis is a bacterial infection. If bacteria reach the bladder, they can multiply and irritate the bladder lining, causing the symptoms of cystitis.

Cystitis can also result from damage or irritation around the urethra. The urethra is the tube that carries urine from the bladder out of the body. In men, the urethral opening (where urine leaves the body) is at the tip of the penis. In women it's just below the clitoris.

Bacterial infection

This happens when bacteria get into the bladder and multiply. It can happen if you don't empty your bladder properly. Try to empty your bladder fully each time you go to the toilet, to help prevent bacterial infection.

You may not be able to empty your bladder fully if:

  • you have a blockage somewhere in your urinary system: this could be caused by a tumour or, in men, an enlarged prostate (a gland located between the penis and the bladder)
  • you are pregnant, as pregnancy puts pressure on the pelvic area and the bladder

Bacterial infection can also happen when bacteria from the anus are transferred to the urethra. This is more common in women than in men, as the urethra is closer to the anus in women than it is in men.

In women, transferring bacteria in this way can happen when you are:

  • having sex
  • wiping after going to the toilet (you're less likely to transfer bacteria in this way if you wipe from front to back)
  • inserting a tampon
  • using a diaphragm (a soft dome made of latex or silicone) for contraception

In women who have had, or are going through, the menopause, the lining of the urethra and the bladder become thinner. This is due to a lack of the hormone oestrogen. The thin lining is more likely to become infected or damaged. Women also produce fewer vaginal secretions after the menopause, which means that bacteria are more likely to multiply.

Damage or irritation

Cystitis can also be caused by damage or irritation in the area around the urethra in both men and women. This could be the result of:

  • damage or bruising caused by vigorous or frequent sex (this is sometimes called honeymoon cystitis)
  • wearing tight clothing
  • chemical irritants – for example, in perfumed soap or talcum powder
  • other bladder or kidney problems, such as a kidney infection or prostatitis
  • diabetes (a long-term condition caused by too much glucose in the blood)
  • damage caused by a catheter (a tube inserted into the urethra to allow urine to flow into a drainage bag, which is often used after surgery)

Find out more about:




  • show glossary terms
Anus
The anus is the opening at the end of the digestive system where solid waste leaves the body.
Bacteria
Bacteria are tiny, single-celled organisms that live in the body. Some can cause illness and disease and some others are good for you.
Catheter
A catheter is a thin, hollow tube usually made of rubber that is placed into the bladder to inject or remove fluid.
Kidney
Kidneys are a pair of bean-shaped organs located at the back of the abdomen, which remove waste and extra fluid from the blood and pass them out of the body as urine.
Prostate
A gland in men located in the pelvis, between the penis and the bladder.
Tumour
A growth of cells.
Urethra
The urethra is a tube that carries urine from the bladder to the outside of the body.

Last reviewed: 04/10/2011

Next review due: 04/10/2013

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