Brain death - Diagnosis 

Diagnosing brain death 

A diagnosis of brain stem death is considered when:

  • a person fails to respond to any outside stimulation
  • the person is unconscious
  • the person's heartbeat and breathing can only be maintained using a ventilator
  • there is clear evidence that serious damage to the brain has occurred, and it cannot be cured

Ruling out other conditions

Before testing for brain stem death can begin, doctors must carry out a series of checks to make sure that the symptoms are not being caused by other factors. Possible factors include:

  • an overdose of illegal drugs, tranquillisers, poisons or other chemical agents
  • having an abnormally low body temperature (hypothermia - symptoms)
  • having a condition that can affect the metabolism (the process that turns food into energy), such as diabetes (a long-term condition caused by too much glucose in the blood) or liver disease (when the liver is damaged, often through drinking excessive amounts of alcohol)

Once these factors have been ruled out, a number of tests are carried out to confirm the diagnosis. The diagnosis of brain stem death has to be made by two senior doctors. Neither of them can be involved with the hospital's transplant team.

The doctors will explain the tests to you, and will keep you informed about your loved one's condition at all times.

Tests

The doctors will run a series of tests. Both of them have to agree on the results for a diagnosis of brain death to be confirmed. The tests are carried out twice to minimise any chance of error.

The tests used to determine whether brain stem death has occurred are outlined below:

  • a torch is shone into both eyes to see if they react to the light
  • the cornea (transparent outer layer of the eye), which is normally very sensitive, is stroked with a tissue or piece of cotton wool
  • pressure is applied to the forehead and the nose is pinched to see if there is any movement in response
  • ice-cold water is squirted into each ear, which would normally cause the eyes to move
  • a thin, plastic tube is place down the trachea (windpipe) to see if this provokes a gagging or coughing reflex
  • the person is withdrawn from the ventilator for a short period of time to see if they make any attempt to breathe on their own

If a person fails to respond to all of these tests, a diagnosis of brain stem death is made.

Occasionally, a person’s limbs or their torso (the upper part of their body) may move, even after brain stem death has been diagnosed. These are spinal reflex movements, which means they are generated by the spinal cord and do not involve the brain at all. These movements will not affect the diagnosis of brain stem death.

  • show glossary terms
Brain stem
The brain stem is the lower part of the brain that is connected to the spinal cord and is responsible for regulating most of the automatic functions of the body that are essential for life, such as breathing.
Liver
The liver is the largest organ in the body. Its main jobs are to secrete bile (to help digestion), detoxify the blood and turn food into energy.
Spinal cord
The spinal cord is a column of nervous tissue located in the spinal column. It sends messages between the brain and the rest of the body.

Last reviewed: 25/05/2010

Next review due: 25/05/2012

Comments are personal views. Any information they give has not been checked and may not be accurate.

iamalady said on 31 October 2010

i also forgot none of the above tests were carried out on my son the doctor just put the DNAR and took away his nutritional tube feed,the doctor said they would take down my sons care in a few hours

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iamalady said on 31 October 2010

can one consultant put a DNAR on a patient when the patient has ards, on a ventilator sedated and paralised by drugs and take the patients care down how can they do this who allows this because this was done to my son so please any answers would be helpful we couldnt stop this, the doctor just went a head but my son lived

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