Your doctor or nurse will discuss with you the need to balance control of your child's asthma with the risk of side effects, and how to keep side effects to a minimum.
Side effects of relievers
Relievers (short-acting beta2 agonists) are safe and effective and have few side effects. The main ones include a mild shaking of the hands, headache and muscle cramps. These usually only happen with high doses of reliever inhalers and do not last very long.
Side effects of preventers
Preventers (corticosteroids), which may be given for asthma as tablets, by injection or through inhalers, can cause a range of side effects. However, when a low-dose corticosteroid is given as a preventer using an appropriate inhaler device, side effects are rare. One side effect of an inhaled steroid given regularly as a preventer is a fungal infection (oral candidiasis or thrush) of the mouth or throat. Very occasionally, children also develop a hoarse voice. Using a spacer can help prevent these side effects. Your child should also rinse their mouth or clean their teeth after taking their preventer inhaler.
During the first year of treatment with an inhaled steroid reliever, there is often a slight slowing of growth. However, with standard doses, children achieve their expected normal adult height. Similarly, regular use of standard doses of a steroid inhaler for several years does not increase the risk of thinning of the bones or of bone fractures.
If your child uses a preventer inhaler for a long time at high doses, there is a small risk of the more serious side effects associated with long-term oral steroid use (see side effects of steroid tablets, below). Children receiving long-term treatment with high doses of an inhaled steroid should be reviewed in a hospital clinic by a specialist respiratory paediatrician.
Side effects of add-on therapy
Some regular treatments for asthma are added when preventer treatment with an inhaled corticosteroid alone does not fully control your child’s symptoms.
Long-acting relievers (long-acting beta2 agonists or LABAs) may cause similar side effects to short-acting relievers: a mild shaking of the hands, headache and muscle cramps. Your GP can discuss the risks and benefits of this medication with you. As with all asthma treatment, your child should be monitored and reviewed regularly. If you feel your child is not benefiting from the use of the long-acting reliever, it should be stopped.
Leukotriene receptor agonists seldom cause side effects but have been known to cause stomach upsets, thirst, headache and occasionally nightmares.
Theophylline tablets are an effective add-on treatment for asthma but commonly cause side effects in children, including nausea, vomiting and stomach upset, headaches, irritability and sleep disturbance.
Side effects of steroid tablets
Children taking oral steroids for more than three months, or who take frequent courses of oral steroids (three to four times a year), are at risk of side effects, these can include:
It is rare for children to need long-term treatment with steroid tablets. Such children should be reviewed at a hospital clinic by a paediatric respiratory specialist. They will require regular examinations to check for the development of these side effects and careful monitoring of their growth in height and weight.
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