When two or more medicines are taken at the same time, the effects of one of the medicines can be altered by the other. This is known as a drug-drug interaction. Some types of antifungal medicines can interact with other medicines.
Tell your GP or pharmacist what other medicines you are taking, including over-the-counter medicines, so that they can decide whether an antifungal medicine is safe for you to take.
Medicines that antifungal medicines may interact with include:
- benzodiazepines – a group of medicines used to help sleep and reduce anxiety
- ciclosporin – a medicine that suppresses the immune system (the body’s natural defence against illness and infection)
- cimetidine – a medicine that is used to treat indigestion
- hydrochlorothiazide – a medicine that is used to treat high blood pressure (hypertension)
- oestrogens – hormones that are found in some contraceptives
- phenytoin – a medicine that is used to treat epilepsy
- progestogens - hormones that are found in some contraceptives
- rifampicin – an antibiotic that is used to treat bacterial infections, such as tuberculosis
- tacrolimus – a medicine that suppresses the immune system
- theophylline – a medicine that is used to treat asthma
- tricyclic antidepressants – medicines that are used to treat depression
- zidovudine – a medicine that is used to treat HIV and AIDS
The above list only includes some examples. See the patient information leaflet that comes with your antifungal medicine, or the Medicines information tab above, for further information about specific medicines and interactions.
