Antifungal medicines - Considerations 

Special considerations 

You are generally advised not to take an antifungal medicine if you are allergic to the medicine or to any of the ingredients that are used in it.

In some cases, such as when treating invasive fungal infections in hospital, your doctors may feel that the benefit of the medicine outweighs the risk of an allergic reaction. They may decide to use the medicine and monitor you closely.

Use antifungals with caution

Be careful with some oral antifungals if you have:

  • problems with your heart 
  • problems with your liver
  • problems with your kidneys

Discuss your condition with your GP or pharmacist to find out which antifungal medicines are safe for you to use.

See the patient information leaflet that comes with your medicine, or the Medicines information tab above, to find out when caution should be used before taking a specific type of antifungal medicine.

Topical antifungals

If you are using a topical antifungal medicine, such as a cream, avoid it coming into contact with:

  • your eyes 
  • mucous membranes (moist linings), for example, inside your nose or mouth (unless it is a gel that is supposed to be used in your mouth)

Contraceptives

Some antifungal medicines are designed to be used on a man's penis or in or around a woman's vagina. Antifungal creams or pessaries are sometimes used to treat thrush.

However, these types of antifungal medicines can damage latex condoms and diaphragms, making them less effective. Use a different method of contraception while you are using the antifungal medicine, or avoid having sex.

Some types of antifungal medicines can also interact with oestrogens and progestogens, which are found in some types of hormonal contraceptives, such as the combined contraceptive pill. You may experience some breakthrough bleeding while taking your antifungal medicine, but your contraceptive protection should not be affected.

Only oral antifungal medicines interact with oestrogens.

Pregnancy

Many antifungal medicines are not suitable to take during pregnancy. Check the patient information leaflet that comes with your medicine to find out.

However, if you have vaginal thrush during pregnancy, your GP may prescribe an antifungal treatment that can be inserted into your vagina (an intravaginal pessary) or an antifungal cream.

Breastfeeding

Small amounts of some medicines can pass into your breast milk and may then be passed on to your baby if you are breastfeeding. Check the patient information leaflet that comes with your antifungal medicine, as many medicines should not be taken while breastfeeding.

  • show glossary terms
Heart
The heart is a muscular organ that pumps blood around the body.
Kidneys
The kidneys are two bean-shaped organs that are located on either side of the body, just underneath the ribcage, that filter out waste products from the blood.
Liver
The liver is the largest organ in the body. Its main jobs are to secrete bile (to help digestion), detoxify the blood and turn food into energy.

Last reviewed: 20/10/2010

Next review due: 20/10/2012

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